Evidence map›Paper›PMID 42910320›Full record

ArticleSensors & diagnostics2025

Comprehensive studies to improve ultrasensitive detection of HIV 1 p24 antigen.

Evan Reboli, Ajoke Williams, Ankan Biswas, Tianwei Jia, Ying Luo, Mukesh Kumar, Suri Iyer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors & diagnostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Evan ReboliDepartment of Chemistry, Kennedy College of Science, University of Massachusetts Lowell, 520 Olney Science Center, Lowell, Massachusetts 01854, USA.
Ajoke WilliamsDepartment of Chemistry, Kennedy College of Science, University of Massachusetts Lowell, 520 Olney Science Center, Lowell, Massachusetts 01854, USA.
Ankan BiswasDepartment of Chemistry, Kennedy College of Science, University of Massachusetts Lowell, 520 Olney Science Center, Lowell, Massachusetts 01854, USA.
Tianwei JiaDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, National Center for Functional Glycomics, CLS 11087-3 Blackfan Circle, Boston, Massachusetts 02115, USA.
Ying LuoDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, 788 Petit Science Center, Atlanta, Georgia 30302, USA.
Mukesh KumarDepartment of Biology, Center for Diagnostics and Therapeutics, Georgia State University, 622 Petit Science Center, Atlanta, Georgia 30302, USA.
Suri IyerDepartment of Chemistry, Kennedy College of Science, University of Massachusetts Lowell, 520 Olney Science Center, Lowell, Massachusetts 01854, USA.

Funding

Towards point of care HIV detection using repurposed glucose metersR33AI140475 · NIAID · UNIVERSITY OF MASSACHUSETTS LOWELL · PI IYER, SURI SARANATHAN · 2022 to 2023
$1.6M
NIAID NIH HHS R33 AI140475
6 · The paper itself

Abstract

Early and accurate detection of HIV-1 p24 antigen is crucial for timely diagnosis and treatment, particularly in resource-limited settings where traditional methods often lack the necessary sensitivity for early-stage detection or is expensive. Here, we developed a layer-by-layer signal amplification platform employing fluorescent silica nanoparticles functionalized

Identifiers

PMID42910320
PMCPMC13686326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.