ArticleTransfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie2026
Platelet Donation by Apheresis for Female Blood Donors with Low Hemoglobin or Iron Deficiency.
Article in Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: In Switzerland, platelet (PLT) donation is allowed with hemoglobin (Hb) ≥110 g/L and ≥120 g/L for women and men, respectively. We report on a policy of proposing PLT apheresis to female donors no longer eligible for whole blood (WB) donation because of low Hb and/or iron deficiency. Methods: We assessed 85 women with Hb <125 g/L and/or ferritin ≤ 15 µg/L who changed to PLT apheresis between 01/1997 and 12/2023 and underwent at least one PLT apheresis/year. Hb and ferritin were evaluated at the first WB donation, at the first and last PLT apheresis and were estimated as adjusted values over 30 PLT donations. Donor retention over a 24-month period was evaluated. Results: The switch to PLT apheresis occurred after a median of 3 (range: 1-33) WB donations. In 42 women (49%), both Hb and ferritin were low, 32 (38%) had low ferritin, and 11 (13%) low Hb only, respectively. Median age (range) at first WB donation and at last PLT donation was 30 years (18-53 years) and 45 years (19-68 years), respectively. Median (range) Hb and ferritin were 134 g/L (120-153 g/L) and 24 µg/L (2-177 µg/L) at the first WB donation and 130 g/L (103-154 g/L) and 14.5 µg/L (3-113 µg/L) at the last PLT apheresis. Over the course of 30 PLT donations and adjusted for donor age, an increasing trend was observed for both Hb (mean + 0.26 g/L; 95% CI: 0.16, 0.35; Conclusion: Women with low Hb and/or iron deficiency benefit from a change to PLT donation and can be retained as regular, highly committed PLT donors.
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