Evidence map›Paper›PMID 42909988›Full record

ArticleInternational journal of biological sciences2026

PEGylated nicotinamide mononucleotide targeted ferroptosis in acute kidney injury by suppressing FAR1 palmitoylation in an ACAA1-dependent manner.

Yang Yue, Changdong Zhou, Qingyu Li, Xiaochang Zhang, Hongjun Lin, Ming Niu, Aihong Zhang, Shuiqin Gong, Lijing Yang, Yuke Cui and 14 more

Abstract read
In one paragraph

Article in International journal of biological sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Yang YueAcademy of Military Medical Sciences, Beijing 100850, China.
Changdong ZhouAcademy of Military Medical Sciences, Beijing 100850, China.
Qingyu LiAcademy of Military Medical Sciences, Beijing 100850, China.
Xiaochang ZhangAcademy of Military Medical Sciences, Beijing 100850, China.
Hongjun LinAcademy of Military Medical Sciences, Beijing 100850, China.
Ming NiuDepartment of Hematology, the Fifth Medical Center of Chinese PLA General Hospital, Beijing 100071, China.
Aihong ZhangDepartment of Nephrology, Chongqing Key Laboratory of Prevention and Treatment of Kidney Disease, Chongqing Clinical Research Center of Kidney and Urology Diseases, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Shuiqin GongDepartment of Nephrology, Chongqing Key Laboratory of Prevention and Treatment of Kidney Disease, Chongqing Clinical Research Center of Kidney and Urology Diseases, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Lijing YangMedical Service Training Center, Chinese PLA General Hospital, Beijing 100853, China.
Yuke CuiPingyuan Laboratory, Henan 453000, China.
Hong ChenAcademy of Military Medical Sciences, Beijing 100850, China.
Xiaodan ChengAcademy of Military Medical Sciences, Beijing 100850, China.
Jiangbo LiAcademy of Military Medical Sciences, Beijing 100850, China.
Qi HeAcademy of Military Medical Sciences, Beijing 100850, China.
Chenhui WangAcademy of Military Medical Sciences, Beijing 100850, China.
Jian LiAcademy of Military Medical Sciences, Beijing 100850, China.
Wen YangAcademy of Military Medical Sciences, Beijing 100850, China.
Jian BaiAcademy of Military Medical Sciences, Beijing 100850, China.
Jingqi ShiAcademy of Military Medical Sciences, Beijing 100850, China.
Yanze LiCapitalBio Technology Corporation, Beijing 101111, China.
Xing QinCapitalBio Technology Corporation, Beijing 101111, China.
Xiangmei ChenDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Liang GuoAcademy of Military Medical Sciences, Beijing 100850, China.
Shengqi WangAcademy of Military Medical Sciences, Beijing 100850, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) remains a major health concern globally, with ferroptosis being the most critical pathological change in proximal tubule cells (PTCs). However, no specific pharmacotherapies have been developed yet. Here, by combining databases (

Indexed as

Acute Kidney InjuryFerroptosisNicotinamide MononucleotidePolyethylene GlycolsAnimalsLipoylationMiceMice, Inbred C57BLNicotinamide MononucleotidePolyethylene GlycolsACAA1acute kidney injuryFAR1 palmitoylationferroptosisNMN

Identifiers

PMID42909988
PMCPMC13685766

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.