Evidence map›Paper›PMID 42909899›Full record

ArticleInternational journal of biological sciences2026

Actin cortex formation is required for integrin clustering but not activation during leukocyte adhesion.

Doulathunnisa Ahamed Younis, Raphael Serna, Wei Liu, Beiyan Zhou, Anthony T Vella, Liang Hu, Yunfeng Chen, Ji Yu, Emanuela M Bruscia, Zhichao Fan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Doulathunnisa Ahamed YounisDepartment of Immunology, School of Medicine, UConn Health, 263 Farmington Ave., Farmington, Connecticut 06030, USA.
Raphael SernaDepartment of Immunology, School of Medicine, UConn Health, 263 Farmington Ave., Farmington, Connecticut 06030, USA.
Wei LiuDepartment of Immunology, School of Medicine, UConn Health, 263 Farmington Ave., Farmington, Connecticut 06030, USA.
Beiyan ZhouDepartment of Immunology, School of Medicine, UConn Health, 263 Farmington Ave., Farmington, Connecticut 06030, USA.
Anthony T VellaDepartment of Immunology, School of Medicine, UConn Health, 263 Farmington Ave., Farmington, Connecticut 06030, USA.
Liang HuAcademy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, 1200 Cai Lun Road, Shanghai 201203, China.
Yunfeng ChenDepartment of Biochemistry and Molecular Biology and Department of Pathology, University of Texas Medical Branch, 301 University Blvd, Galveston, Texas 77555, USA.
Ji YuCenter for Cell Analysis and Modeling, UConn Health, 263 Farmington Ave., Farmington, Connecticut 06030, USA.
Emanuela M BrusciaDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Zhichao FanDepartment of Immunology, School of Medicine, UConn Health, 263 Farmington Ave., Farmington, Connecticut 06030, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukocyte recruitment is critical for tissue homeostasis and inflammatory responses. Chemokine-induced β

Indexed as

Actin CytoskeletonActinsIntegrinsLeukocytesAnimalsCell AdhesionCytochalasin DHumansMiceMonocytesActinsCytochalasin DIntegrinsactin cortexCORO1Aintegrin activationintegrin clusteringmonocyte adhesionβ2 integrins

Identifiers

PMID42909899
PMCPMC13685610

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.