Evidence map›Paper›PMID 42909724›Full record

ArticleThe international journal of cardiovascular imaging2026

Cardiovascular Magnetic Resonance in MINOCA and Acute Myocarditis: A Comparative Multiparametric Evaluation.

Chiara Tognola, Francesca Daus, Stefano Pedroli, Davide Bernasconi, Paola Sormani, Ilaria Bassi, Angela Milazzo, Giuseppina Quattrocchi, Cristina Giannattasio, Patrizia Pedrotti

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Article in The international journal of cardiovascular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Chiara TognolaSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy. chiara.tognola@ospedaleniguarda.it.ORCID http://orcid.org/0009-0003-7782-8949
Francesca DausCardiologia IV, De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Piazza dell'Ospedale Maggiore, 3, Milan, 20162, Italy.
Stefano PedroliSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Davide BernasconiSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Paola SormaniCardiologia IV, De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Piazza dell'Ospedale Maggiore, 3, Milan, 20162, Italy.
Ilaria BassiCardiologia IV, De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Piazza dell'Ospedale Maggiore, 3, Milan, 20162, Italy.
Angela MilazzoCardiologia IV, De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Piazza dell'Ospedale Maggiore, 3, Milan, 20162, Italy.
Giuseppina QuattrocchiCardiologia IV, De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Piazza dell'Ospedale Maggiore, 3, Milan, 20162, Italy.
Cristina GiannattasioSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Patrizia PedrottiCardiologia IV, De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Piazza dell'Ospedale Maggiore, 3, Milan, 20162, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction with non-obstructive coronary arteries (MINOCA) and acute myocarditis (AM) often present with overlapping clinical features and biomarker profiles, making early differential diagnosis challenging. Cardiovascular magnetic resonance (CMR) is the reference modality for etiological assessment through functional evaluation and multiparametric tissue characterization. The aim of this study was to compare clinical and CMR characteristics of patients with MINOCA and suspected AM, and to identify imaging features enabling accurate differentiation. We retrospectively analyzed 127 consecutive patients undergoing CMR (February 2021-October 2024): 62 with suspected MINOCA and 65 with suspected AM. Clinical data, laboratory findings, ECG, and CMR parameters (cine imaging, T1/T2 mapping, extracellular volume [ECV], and late gadolinium enhancement [LGE]) were assessed. MINOCA patients were older (median 59 years) and predominantly female (64.5%), whereas AM patients were younger (median 29 years) and mainly male (81.5%). AM was associated with higher troponin and inflammatory markers. Among patients initially referred with suspected MINOCA, LGE was present in 50.0%, compared with 93.8% of those referred with suspected acute myocarditis (p < 0.001). MINOCA showed predominantly ischemic LGE patterns, while AM exhibited non-ischemic subepicardial or mid-wall LGE with myocardial edema. CMR confirmed myocardial infarction in 48.4% of patients and identified alternative diagnoses in 41.9%, while 9.7% had normal CMR findings. Multiparametric CMR reliably distinguishes ischemic from inflammatory myocardial injury in patients with chest pain, elevated troponin, and non-obstructive coronaries. Early CMR integration improves diagnostic accuracy and supports tailored management.

Indexed as

Acute MyocarditisCardiac Magnetic ResonanceLate Gadolinium EnhancementMyocardial Infarction Non-Obstructive Coronary ArteriesTissue Characterization

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.