ArticleBreast cancer research and treatment2026
Change in alcohol consumption and all-cause mortality among postmenopausal women diagnosed with breast cancer.
Article in Breast cancer research and treatment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
purposeEvidence is inconsistent regarding an association between alcohol consumption and survival following a breast cancer diagnosis; therefore, we examined how change in alcohol consumption affects all-cause mortality (ACM) in a population of breast cancer survivors.
methodsWe prospectively assessed pre-diagnosis, pre- to post-diagnosis, and post-diagnosis change in alcohol consumption among 1,558 postmenopausal women (mean age-at-diagnosis: 71 years) diagnosed with non-metastatic invasive breast cancer from the American Cancer Society Cancer Prevention Study-II Nutrition Cohort (baseline: 1992-1993). Five categories of alcohol intake were determined at each assessment; change in alcohol consumption was categorized as stable, quit, reduced, and increased. Change occurred at a median of two years before (pre-diagnosis) and two years after (post-diagnosis) diagnosis. Cox proportional hazards regression was used to estimate adjusted hazard ratios (HR) and 95% confidence intervals (CI) for the associations between change groups and ACM.
resultsOver a median follow-up of 12.6 years, 750 women died (130 breast cancer deaths). Compared to stable consumption, the association between cessation and ACM varied by change interval: pre-diagnosis (HR:0.91, CI:0.69-1.21), pre- to post-diagnosis: (HR:1.39, CI:1.12-1.73), post-diagnosis: (HR:0.98, CI:0.70-1.35). Alcohol reduction was not associated with ACM. Among women consuming ≥ 1 drink/day pre-diagnosis, increasing consumption elevated ACM risk (HR:1.83, 95%CI:1.02-3.31).
conclusionAlcohol reduction or cessation was not associated with a decrease in ACM among older breast cancer survivors. Among those drinking ≥ 1 drink/day, an increase in consumption pre-diagnosis was associated with higher mortality. Findings may be limited by uncontrolled confounding, a low prevalence of heavy drinking, or an insufficient duration of sustained change.
Indexed as
Identifiers
42909681What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.