Evidence map›Paper›PMID 42909665›Full record

ArticleArchives of virology2026

Epigallocatechin gallate inhibits rabies virus glycoprotein‑mediated infection in vitro.

Denis Pasqual, Maria Francesca Priore, Silvia Fabi, Yasaman Shamsizadeh, Maira Zorzan, Chiara Rampazzo, Marta Trevisan, Arianna Loregian, Claudia Del Vecchio, Paola De Benedictis and 1 more

Abstract read
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Article in Archives of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Denis PasqualDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Maria Francesca PrioreDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Silvia FabiDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Yasaman ShamsizadehDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Maira ZorzanNational and FAO Reference Center for Rabies, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padua, Italy.
Chiara RampazzoDepartment of Biology, University of Padua, Padua, Italy.
Marta TrevisanDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Arianna LoregianDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Claudia Del VecchioDepartment of Molecular Medicine, University of Padua, Padua, Italy.
Paola De BenedictisNational and FAO Reference Center for Rabies, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padua, Italy.
Cristiano SalataDepartment of Molecular Medicine, University of Padua, Padua, Italy. cristiano.salata@unipd.it.ORCID https://orcid.org/0000-0002-5136-7406

Funding

Ministero dell'Università e della Ricerca PE00000007
6 · The paper itself

Abstract

Rabies is one of the most lethal zoonotic disease and causes approximately 60,000 human deaths annually. The high cost of immunoglobulin prophylaxis and the need for cold chain maintenance highlight the need for accessible antiviral strategies, particularly in resource-limited settings. Epigallocatechin gallate (EGCG), the major polyphenolic compound of Camellia sinensis, has broad-spectrum antiviral activity. We therefore investigated its activity against Rabies virus (RABV). Because RABV requires BSL-3 containment, we first used a recombinant Vesicular Stomatitis Virus pseudotyped with RABV glycoprotein (pRABV) as a surrogate. EGCG inhibited pRABV infection in a concentration-dependent manner, with an EC

Indexed as

Antiviral AgentsCatechinGlycoproteinsRabies virusAnimalsCell LineHumansRabiesVirus AttachmentVirus InternalizationAntiviral AgentsCatechinepigallocatechin gallateGlycoproteins

Identifiers

PMID42909665

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.