ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2026
An investigation of dental anomalies in individuals with amelogenesis imperfecta.
Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo explore the presence of dental anomalies in children with amelogenesis imperfecta (AI) and to describe their distribution across different AI genetic variants.
methodsThis cross-sectional study undertook secondary analysis of data from a primary study of children with AI below 18 years of age. After training and calibration, participants' panoramic radiographs and clinical photographs were assessed for the presence of six dental anomalies (pre-eruptive crown resorption, eruption abnormalities, pulp calcifications, taurodontism, gingival enlargement and anterior open bite). The enamel phenotype was assessed. Dental age was estimated using the Demirjian method and compared with chronological age. The genetic diagnosis, where available, was mapped to the identified dental anomalies.
resultsThirty participants were assessed (16 male, 14 female). Twenty-one (70.0%) had hypomineralised enamel and 9 (30.0%) had hypoplastic enamel. Twenty-two (73.3%) had at least one dental anomaly in addition to the enamel phenotype. One participant was excluded from dental age analysis. Sixteen participants (55.2%) had advanced dental age, 12 (41.4%) had delayed dental age, one had matching ages (3.4%). Twenty-six participants (89.7%) had a dental age within 18 months of their chronological age. Thirteen individuals had known molecular causes for their AI, including FAM83H, LAMB3, ENAM, COL17A1, AMBN, MMP20 and SP6. Amongst these individuals, a range of the dental anomalies considered were observed.
conclusionSeveral dental anomalies were found to occur alongside AI. Dental age did not appear to vary substantially from chronological age. Dental anomalies should be considered as part of comprehensive clinical and radiographic assessment for those with AI.
Indexed as
Identifiers
42909575What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.