Evidence map›Paper›PMID 42909564›Full record

ArticleVeterinary research communications2026

Revisiting porcine circovirus infections in Uruguay: first evidence of PCV3 circulation and PCV2d as the sole genotype detected.

Natalia Ramos, Axel Galiano, Gabriela Betancour, Luiz Gustavo Schneider de Oliveira, Florencia Buroni, Fabiana Boabaid, Juan Arbiza

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Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natalia RamosSección Virología, Facultad de Ciencias, Universidad de la República, Iguá 4225, 11400, Montevideo, Uruguay. nramos@fcien.edu.uy.ORCID http://orcid.org/0000-0003-1355-9463
Axel GalianoSección Virología, Facultad de Ciencias, Universidad de la República, Iguá 4225, 11400, Montevideo, Uruguay.
Gabriela BetancourSección Virología, Facultad de Ciencias, Universidad de la República, Iguá 4225, 11400, Montevideo, Uruguay.
Luiz Gustavo Schneider de OliveiraInstituto Nacional de Investigación Agropecuaria (INIA), Plataforma de Investigation en Salud Animal, Estación Experimental INIA Tacuarembó, Tacuarembó, Uruguay.
Florencia BuroniDivisión de Laboratorios Veterinarios Miguel C. Rubino. Regional Norte, Ministerio de Ganadería Agricultura y Pesca (MGAP), Tacuarembó, Uruguay.
Fabiana BoabaidPolo de Desarrollo Universitario del Instituto Superior de la Carne, Centro Universitario Regional (CENUR), Noreste, Universidad de la República, Tacuarembó, Uruguay.
Juan ArbizaSección Virología, Facultad de Ciencias, Universidad de la República, Iguá 4225, 11400, Montevideo, Uruguay.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine circoviruses (PCVs) are widespread among pig populations, and porcine circovirus type 2 (PCV2) is a major pathogen affecting swine health and productivity worldwide. Although PCV2 genetic diversity was previously characterized in Uruguay, updated information has been lacking for more than a decade, and porcine circovirus type 3 (PCV3) has not been reported. This study aimed to characterize recent PCV2 clinical cases and retrospectively investigate PCV3 circulation in archived samples previously analysed for PCV2. Complete PCV2 genomes obtained from clinical cases detected between 2017 and 2020 belonged to PCV2d. PCV3 was detected in archived samples from 2010 to 2014, including domestic pigs and wild boars, providing the first evidence of PCV3 circulation in Uruguay. All characterized PCV3 strains clustered within PCV3a, and PCV2/PCV3 coinfection was observed in several PCV3-positive samples. These findings indicate that PCV2d predominated among the investigated clinical cases from non-vaccinated farms and confirm PCV3 circulation in Uruguay, making it the fifth South American country to report the virus. Continued molecular surveillance is warranted to monitor PCV2 and PCV3 diversity and better understand the epidemiology of PCVs in Uruguay and across South America.

Indexed as

Circoviridae InfectionsCircovirusGenotypeSwine DiseasesAnimalsGenetic VariationPhylogenyRetrospective StudiesSus scrofaSwineUruguayGenetic diversityPCV2dPCV3Porcine circovirus infectionsSouth America

Identifiers

PMID42909564

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.