Evidence map›Paper›PMID 42909386›Full record

ReviewInternational journal of medical sciences2026

Metabolomics in the Prediction and Early Diagnosis of Type 2 Diabetes Mellitus: Advances and Applications.

Xiaokai Wei, Min He, Haili Wang, Xin Xiang, Mengyuan Li, Mengmeng Li, Thanh Tuan Vu Le, Zhongxian Wang, Dingqi Zhang, Lei Cheng and 2 more

Abstract readReview
In one paragraph

Review in International journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaokai WeiCollege of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Min HeJilin Provincial International Cooperation Key Laboratory of Traditional Medicine for Prevention and Treatment of Metabolic Diseases, Changchun University of Chinese Medicine, Jingyue Economic Development District, Changchun, Jilin, China.
Haili WangCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Xin XiangCollege of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Mengyuan LiJilin Provincial International Cooperation Key Laboratory of Traditional Medicine for Prevention and Treatment of Metabolic Diseases, Changchun University of Chinese Medicine, Jingyue Economic Development District, Changchun, Jilin, China.
Mengmeng LiCollege of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Thanh Tuan Vu LeCollege of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Zhongxian WangCollege of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Dingqi ZhangCollege of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Lei ChengCollege of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Mengmeng SunJilin Provincial International Cooperation Key Laboratory of Traditional Medicine for Prevention and Treatment of Metabolic Diseases, Changchun University of Chinese Medicine, Jingyue Economic Development District, Changchun, Jilin, China.
Hongfeng WangJilin Provincial International Cooperation Key Laboratory of Traditional Medicine for Prevention and Treatment of Metabolic Diseases, Changchun University of Chinese Medicine, Jingyue Economic Development District, Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early detection and intervention can prevent the onset and progression of type 2 diabetes mellitus (T2DM); however, achieving early diagnosis and accurate prediction remains challenging. Metabolomics, a potent diagnostic tool in systems biology, makes it possible to systematically identify important biomarkers linked to type 2 diabetes, which provides vital proof for risk assessment and early diagnosis. This review summarizes research advances in metabolomics for T2DM prediction and early detection since 2010 by incorporating both the reported prospective and cross-sectional metabolic evidence, with a focus on putative biomarkers and their metabolic characteristics identified across diverse biological samples. Furthermore, it highlights the unique advantages of metabolomics in T2DM early warning, aiming to offer novel insights for future research on personalized prevention and early diagnostic strategies.

Indexed as

Diabetes Mellitus, Type 2MetabolomicsBiomarkersEarly DiagnosisHumansRisk AssessmentBiomarkersbiomarkersdiabetesearly diagnosismetabolomicspredictionsample

Identifiers

PMID42909386
PMCPMC13685039

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.