Evidence map›Paper›PMID 42909320›Full record

ArticleFrontiers in medicine2026

Artificial intelligence for ultrasound-based differentiation of soft tissue liposarcoma from benign masses.

YuKun Deng, Chengjia Qu, Yi Cao, Guoyang Yu, Jingmiao Yu, Jie Yang, Wen Guo, Dandan Wang, Xiaoting Qin, Yibing Zhao and 1 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

YuKun Deng *Department of Medical Ultrasonics, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.
Chengjia Qu *Department of Vascular Surgery, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.
Yi CaoDepartment of Medical Ultrasonics, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.
Guoyang YuDepartment of Medical Ultrasonics, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.
Jingmiao YuDepartment of Medical Ultrasonics, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.
Jie YangDepartment of Medical Ultrasonics, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.
Wen GuoDepartment of Medical Ultrasonics, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.
Dandan WangDepartment of Medical Ultrasonics, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.
Xiaoting QinDepartment of Medical Ultrasonics, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.
Yibing ZhaoDepartment of Medical Ultrasonics, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.
Tao ChenDepartment of Medical Ultrasonics, Beijing Jishuitan Hospital Affiliated to Capital Medical University, National Center for Orthopedics, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Accurate preoperative differentiation of liposarcoma from benign masses on ultrasound remains challenging and operator-dependent. We aimed to develop and validate a deep learning-based model to assist in distinguishing liposarcoma from benign masses. Methods: In this retrospective single-center study, we collected B-mode ultrasound examinations from patients with soft tissue masses between March 2015 and March 2022 at Beijing Jishuitan Hospital affiliated to Capital Medical University. A two-stage deep convolutional neural network was developed: a U-Net model segmented tumor regions, followed by a ResNet50 classifier for tumor type prediction. The cohort ( Results: Among 317 cases, 191 were benign masses and 126 were liposarcomas. In the internal test set, the AI model achieved an AUC of 0.97 (95% CI 0.92-1.00), an accuracy of 0.97 (95% CI 0.93-1.00), a sensitivity of 0.96 (95% CI 0.86-1.00), and a specificity of 0.97 (95% CI 0.93-1.00). AI achieved significantly higher accuracy than both residents after Holm adjustment (adjusted Conclusions: A two-stage deep learning model using ultrasound images showed preliminary potential for differentiating liposarcoma from benign masses in this single-center cohort. External validation is required before clinical use.

Indexed as

artificial intelligenceliposarcomaResNet50ultrasoundu-net

Identifiers

PMID42909320
PMCPMC13684072

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.