Evidence map›Paper›PMID 42909312›Full record

ReviewFrontiers in genetics2026

Chromatin remodeling in bone organoids: from epigenetic regulation to disease modeling and therapeutic translation.

Yuxin Zheng, Desheng Liu, Jun Hou, Hong Ding, Yingying He

Abstract readReview
In one paragraph

Review in Frontiers in genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuxin Zheng *School of Clinical Medicine, Qiqihar Medical University, Qiqihar, China.
Desheng Liu *Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.
Jun HouSchool of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China.
Hong DingOrthopedic Center, Liangjiang Hospital Affiliated to Chongqing Medical University, Chongqing, China.
Yingying HeJiulongpo District Maternal and Child Healthcare Hospital, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromatin remodeling contributes to skeletal development, tissue homeostasis, and disease by regulating nucleosome positioning, chromatin accessibility, and histone modifications. Bone organoids can partially reproduce the three-dimensional human bone microenvironment and provide new

Indexed as

bone disease modelingbone organoidschromatin remodelingepigenetic regulationskeletal development

Identifiers

PMID42909312
PMCPMC13684075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.