ArticleFrontiers in public health2026
Associations of social support and disease-specific quality of life with self-management among patients with chronic hepatitis B: a multicenter cross-sectional study.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Self-management behaviors are central to long-term care for chronic hepatitis B (CHB), but the independent associations of social support and disease-specific quality-of-life domains with self-management remain unclear. This study assessed self-management and its associated factors among patients with CHB. Methods: This multicenter cross-sectional study included 583 patients with CHB recruited by convenience sampling at three tertiary hospitals in Hengyang, China, from March to October 2025. Participants completed the Chronic Hepatitis B Self-Management Scale (CHBSMS), Social Support Rating Scale (SSRS), and Chronic Hepatitis B Quality of Life Instrument (CHBQOL). Hierarchical multiple linear regression, HC3 robust standard errors, and sensitivity analyses were used. Results: The mean total CHBSMS score was 85.03 ± 19.38. The sociodemographic model yielded an Conclusion: Among patients with CHB recruited from three tertiary hospitals, social support, the emotional symptoms domain, and the social stigma domain were associated with self-management after adjustment for sociodemographic, clinical, and healthcare utilization factors. Further longitudinal research is needed to clarify the temporal direction and clinical relevance of these associations.
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