ArticleFrontiers in medicine2026
Associations of insulin resistance-related metabolic indices with albuminuria in primary hypertension without diabetes: a retrospective cross-sectional study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Insulin resistance-related metabolic indices have been associated with albuminuria in general populations and in patients with diabetes, but evidence in patients with primary hypertension without diabetes remains limited. Whether mean arterial pressure (MAP) statistically accounts for part of these associations is unclear. Methods: We retrospectively analysed cross-sectional data from 509 hospitalised cardiology patients with primary hypertension without diabetes at a single tertiary centre who underwent urinary albumin-to-creatinine ratio (UACR) testing. Albuminuria was defined as a UACR ≥30 mg/g. Associations of the triglyceride-glucose body mass index (TyG-BMI), metabolic score for insulin resistance (METS-IR), and triglyceride-glucose (TyG) index with albuminuria and log Results: Among the 509 participants, 99 (19.4%) had albuminuria. After multivariable adjustment, the odds ratios (ORs) for albuminuria per 1-SD increment in TyG-BMI, METS-IR, and the TyG index were 1.610 [95% confidence interval (CI), 1.262-2.055], 1.557 (95% CI, 1.215-1.995), and 1.436 (95% CI, 1.128-1.829), respectively. Corresponding Q4-vs.-Q1 ORs were 2.464 (95% CI, 1.228-4.943), 2.665 (95% CI, 1.268-5.600), and 2.137 (95% CI, 1.092-4.181), with overall categorical Conclusions: Higher TyG-BMI, METS-IR, and TyG index values were associated with albuminuria and higher UACR in patients with primary hypertension without diabetes. Exploratory analyses suggested statistical indirect components involving MAP for TyG-BMI and METS-IR, but did not establish temporal ordering or causal mediation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.