ArticleFrontiers in oncology2026
Laparoscopic para-aortic and pelvic lymphadenectomy before chemoradiotherapy was not associated with improved survival in patients with FIGO stage IIB-IIIC cervical cancer: a single-center retrospective study.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Currently, whether surgical staging can confer a survival benefit in patients with cervical cancer remains controversial, and its efficacy is similarly uncertain across different subgroups. The primary aim of this study was to assess the efficacy of laparoscopic para-aortic and pelvic lymphadenectomy prior to chemoradiotherapy in patients with International Federation of Gynecology and Obstetrics (FIGO) stage IIB-IIIC cervical cancer. The secondary aim was to identify the main prognostic factors. Methods: A total of 396 patients were included in this retrospective study, 97 patients who underwent laparoscopic para-aortic and pelvic lymphadenectomy before chemoradiotherapy comprised the surgical staging group, and 299 patients who received chemoradiotherapy alone comprised the clinical staging group. Kaplan-Meier and log-rank methods were used to construct and compare progression-free survival (PFS) and overall survival (OS) curves, respectively. Multivariable Cox proportional hazards regression models were used to identify independent prognostic factors. Results: There were no statistically significant differences in PFS ( Conclusions: Laparoscopic para-aortic and pelvic lymphadenectomy before chemoradiotherapy was not associated with improved PFS or OS in this retrospective cohort, Tumor histology, pelvic wall involvement, and imaging-positive lymph nodes were the main prognostic factors.
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