Evidence map›Paper›PMID 42908738›Full record

ArticleiMeta2026

Artificial intelligence models Traditional Chinese Medicine principles to integrate with biomedicine.

Haoran Li, Xingye Cheng, Ziyang Huang, Jingyuan Luo, Qianqian Xu, Qiguang Zhao, Tianchen Guo, Yumeng Zhang, Linda L D Zhong, Zhaoxiang Bian and 3 more

Abstract readLetter
In one paragraph

Article in iMeta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Haoran LiDepartment of Physics Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0000-0001-8140-8910
Xingye ChengDepartment of Physics Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0000-0002-9996-455X
Ziyang HuangDepartment of Physics Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0000-0002-7182-9188
Jingyuan LuoSchool of Chinese Medicine, Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0000-0001-8036-7918
Qianqian XuSchool of Chinese Medicine, Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0000-0002-8124-6277
Qiguang ZhaoSchool of Chinese Medicine, Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0009-0001-5497-3217
Tianchen GuoSchool of Chinese Medicine, Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0009-0005-6220-3895
Yumeng ZhangSchool of Chinese Medicine, Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0009-0001-9204-7783
Linda L D ZhongSchool of Biological Sciences, Nanyang Technological University Singapore Singapore.ORCID https://orcid.org/0000-0002-3877-1914
Zhaoxiang BianVincent V.C. Woo Chinese Medicine Clinical Research Institute, Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0000-0001-6206-1958
Leihan TangCenter for Interdisciplinary Studies and School of Science, Westlake University Hangzhou China.ORCID https://orcid.org/0000-0002-2925-4691
Aiping LyuSchool of Chinese Medicine, Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0000-0002-2303-0494
Liang TianDepartment of Physics Hong Kong Baptist University Hong Kong SAR China.ORCID https://orcid.org/0000-0002-6595-445X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using 26,339 model-eligible Traditional Chinese Medicine (TCM) formula records, we trained an autoencoder following TCM's compression-expansion logic to learn the TCM embedding space (TCM-ES), quantifying symptom-pattern-formula mappings. TCM-ES aligns with conventional TCM principles not used in training. Biomedical entities were mapped post hoc into the fixed space, supporting formula prediction, retrospective clinical analyses, and exploratory therapeutic prioritization.

Identifiers

PMID42908738
PMCPMC13683242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.