ArticleFrontiers in neurology2026
Risk factors for postoperative recurrence of chronic subdural hematoma and construction and validation of an online dynamic nomogram prediction model.
Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate factors associated with postoperative recurrence in patients with chronic subdural hematoma (CSDH) and to construct and internally validate an online dynamic nomogram for individualized recurrence-risk estimation. Methods: This retrospective single-center study included 284 surgically treated patients with CSDH between January 2018 and May 2025. Before model development, the cohort was divided at a 7:3 ratio into a training cohort ( Results: Overall, 54 of 284 patients (19.01%) experienced recurrence; 33 recurrence events occurred in the training cohort and 21 in the validation cohort. Smoking history, laterality, hematoma density, greatest hematoma thickness, cerebral midline shift ≥10 mm, and postoperative pneumocephalus were statistically significant in the multivariable analysis. The AUC was 0.89 (95% CI, 0.82-0.95, sensitivity 0.82, specificity 0.85) in the training cohort and 0.74 (95% CI, 0.59-0.88, sensitivity 0.52, specificity 0.85) in the validation cohort. Bootstrap optimism correction yielded an apparent AUC of 0.892, a mean optimism of 0.021, and an optimism-corrected AUC of 0.871. In the training cohort, the Hosmer-Lemeshow test showed no statistically significant evidence of lack of fit ( Conclusion: The online nomogram provides a convenient framework for individualized recurrence risk estimation. Further external multicenter validation is warranted to assess its generalizability and clinical applicability.
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