Evidence map›Paper›PMID 42908731›Full record

ArticleFrontiers in neurology2026

Risk factors for postoperative recurrence of chronic subdural hematoma and construction and validation of an online dynamic nomogram prediction model.

Xiangyu Zhang, Zhicheng Huang, Sai Li, Binghui Wu, Mingjun Li, Hongliang Wang, Bing Zhao, Zhifei Guo

Abstract readValidation Study
In one paragraph

Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Xiangyu ZhangDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhicheng HuangDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Sai LiDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Binghui WuDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Mingjun LiDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Hongliang WangDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Bing ZhaoDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhifei GuoDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate factors associated with postoperative recurrence in patients with chronic subdural hematoma (CSDH) and to construct and internally validate an online dynamic nomogram for individualized recurrence-risk estimation. Methods: This retrospective single-center study included 284 surgically treated patients with CSDH between January 2018 and May 2025. Before model development, the cohort was divided at a 7:3 ratio into a training cohort ( Results: Overall, 54 of 284 patients (19.01%) experienced recurrence; 33 recurrence events occurred in the training cohort and 21 in the validation cohort. Smoking history, laterality, hematoma density, greatest hematoma thickness, cerebral midline shift ≥10 mm, and postoperative pneumocephalus were statistically significant in the multivariable analysis. The AUC was 0.89 (95% CI, 0.82-0.95, sensitivity 0.82, specificity 0.85) in the training cohort and 0.74 (95% CI, 0.59-0.88, sensitivity 0.52, specificity 0.85) in the validation cohort. Bootstrap optimism correction yielded an apparent AUC of 0.892, a mean optimism of 0.021, and an optimism-corrected AUC of 0.871. In the training cohort, the Hosmer-Lemeshow test showed no statistically significant evidence of lack of fit ( Conclusion: The online nomogram provides a convenient framework for individualized recurrence risk estimation. Further external multicenter validation is warranted to assess its generalizability and clinical applicability.

Indexed as

Hematoma, Subdural, ChronicNomogramsPostoperative ComplicationsAgedAged, 80 and overFemaleHumansMaleMiddle AgedRecurrenceRetrospective StudiesRisk Factorschronic subdural hematomaonline dynamic nomogrampostoperative recurrenceprediction modelrisk factors

Identifiers

PMID42908731
PMCPMC13683128

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.