Evidence map›Paper›PMID 42908637›Full record

ArticleFrontiers in microbiology2026

Sequence-activity mapping and model-guided engineering of the phenol-responsive DmpR-Po σ

Yuxi Xu, Mingxuan Song, Wenglong Xing, Jianying Han, Jiahao Wu, Yi Cheng, Jiayi Liu, Linfeng Wang, Ji Zeng, Yu Zhao and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuxi XuSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Mingxuan SongSchool of Computer Science and Technology, Guangdong University of Technology, Guangzhou, China.
Wenglong XingSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Jianying HanSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Jiahao WuSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Yi ChengSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Jiayi LiuSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Linfeng WangSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Ji ZengSchool of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Yu ZhaoGuangdong Provincial Key Laboratory of Functional Soft Condensed Matter, School of Material and Energy, Guangdong University of Technology, Guangzhou, China.
Jinquan GuoDepartment of Breast and Thyroid Surgery, The Affiliated Panyu Central Hospital, Guangzhou Medical University, Guangzhou, China.
Shuting CaiSchool of Integrated Circuits, Guangdong University of Technology, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Promoters are core cis-regulatory elements that determine gene expression levels and dynamic responses, and their quantitative engineering directly dictates the performance of synthetic biological systems such as whole-cell biosensors. However, the transcriptional output of complex inducible systems, exemplified by σ

Indexed as

DeepSHAPDmpR–PoFACS-seqin silico mutagenesismachine learningpromoter engineeringσ54 promoter

Identifiers

PMID42908637
PMCPMC13682980

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.