Evidence map›Paper›PMID 42908635›Full record

SynthesisFrontiers in physiology2026

Antioxidant but not ergogenic or altitude-protective: a meta-analysis of Rhodiola species in healthy adults.

Jie Mou, Jingxian Yin, Lingting Fan, Wen Zhang, Junxian He, Hongyu Sun

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie MouCollege of Medicine, Southwest Jiaotong University, Chengdu, China.
Jingxian YinCollege of Medicine, Southwest Jiaotong University, Chengdu, China.
Lingting FanCollege of Medicine, Southwest Jiaotong University, Chengdu, China.
Wen ZhangCenter for Animal Experimentation, Clinical Biobank, and Bioinformatics, The General Hospital of Western Theater Command, Chengdu, China.
Junxian HeCenter for Animal Experimentation, Clinical Biobank, and Bioinformatics, The General Hospital of Western Theater Command, Chengdu, China.
Hongyu SunCollege of Medicine, Southwest Jiaotong University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Plants of the genus Methods: Nine Randomized Controlled Trials (RCTs, n=424) were identified from PubMed, Cochrane, Medline, and China National Knowledge Infrastructure (CNKI). Primary outcomes included maximal oxygen uptake (VO Results: R. rosea significantly increased TAC (P=0.02) and showed a trend toward reducing TBARS levels (P=0.06), indicating enhanced systemic antioxidant capacity. However, it showed no significant effect on VO Conclusion: Extracts of Rhodiola species significantly improves systemic antioxidant status and may alleviate high-altitude de-adaptation symptoms. However, current evidence does not support its efficacy for improving VO Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251004228, identifier CRD420251004228.

Indexed as

antioxidant capacitymeta-analysisplateau acclimatization/deacclimatizationRhodiola roseaRhodiola species

Identifiers

PMID42908635
PMCPMC13682997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.