ReviewJournal of ovarian research2026
From cytoreduction to precision oncology: evolution of ovarian cancer therapy.
Review in Journal of ovarian research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
No citing paper in PubMed yet.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ovarian cancer remains the most lethal gynecologic malignancy due to its asymptomatic progression, limited screening modalities, and late-stage diagnosis. Although initial responses to platinum-based chemotherapy are common, recurrence and multidrug resistance are nearly universal, necessitating a shift toward biomarker-guided, precision-based interventions. This review synthesizes current evidence on the evolving landscape of ovarian cancer treatment, with emphasis on molecular pathogenesis, histotype-specific vulnerabilities, and advances in therapeutic strategies. Focus is placed on the clinical integration of poly (ADP-ribose) polymerase (PARP) inhibitors, vascular endothelial growth factor (VEGF)-targeting agents, immune checkpoint inhibitors, and antibody-drug conjugates, alongside emerging platforms such as liquid biopsy, artificial intelligence-enhanced diagnostics, and histotype-driven targeted therapies. Translational insights from other malignancies were utilized to highlight future directions for ovarian cancer, including dual pathway targeting, immune and epigenetic modulation, and receptor-guided cytotoxic delivery. Collectively, these advances demonstrate how precision oncology is advancing ovarian cancer treatment, with the potential to improve survival outcomes while preserving quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.