SynthesisBMC cancer2026
Optimizing exercise regimens for quality of life in patients with cancer: a network meta-analysis and dose-response study.
Synthesis in BMC cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveTo systematically evaluate the effects and dose-response relationships of different exercise interventions in improving the quality of life of patients with cancer using a combined Bayesian network meta-analysis and network dose-response meta-analysis approach.
methodsSystematic searches were conducted in PubMed, Web of Science, Embase, and the Cochrane Library (up to August 2026). Interventions were ranked using the surface under the cumulative ranking curve (SUCRA), and dose-response relationships were modelled using the Emax model.
resultA total of 149 randomized controlled trials involving 13,004 patients with cancer were included. Network meta-analysis showed that Qigong/Tai Chi, high-intensity interval training (HIIT), and combined aerobic and resistance training were the highest-ranked interventions according to SUCRA. Model-based dose-response analysis suggested a nonlinear association between exercise dose and quality of life, with the model-estimated overall effect peaking at approximately 2000 MET-min/week. Qigong/Tai Chi was associated with significant improvements at lower doses (750 MET-min/week), whereas HIIT and combined aerobic and resistance training showed model-estimated maximum effects at 800 and 2000 MET-min/week, respectively.
conclusionThis study compared exercise modalities and dose-response characteristics, identifying model-derived dose estimates associated with the greatest quality-of-life improvements in patients with cancer. These estimates may inform the scientific application of exercise interventions in cancer rehabilitation but require prospective validation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.