Evidence map›Paper›PMID 42907759›Full record

ArticleBMC microbiology2026

Bioprocessing of Talaromyces purpurogenus for production of dihydromonascorubrin with a powerful antioxidant and antimicrobial activities integrated with the network-guided target prediction and molecular docking analyses.

Ashraf S A El-Sayed, Samar A Khashana, Sobhy S Abdel-Fatah, Abeer Eldeghidy, Nouran A Abd El-Hady, Ashraf F El-Baz, Manal A El-Shal, Eman Fikry, Rawia A Zayed, Wafaa M Ismaeil

Abstract read
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In one paragraph

Article in BMC microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashraf S A El-SayedEnzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt. ash.elsayed@gmail.com.ORCID https://orcid.org/0000-0002-2261-333X
Samar A KhashanaEnzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
Sobhy S Abdel-FatahDrug Radiation Research Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, Cairo, Egypt.
Abeer EldeghidyEnzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
Nouran A Abd El-HadyEnzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
Ashraf F El-BazDepartment of Industrial Biotechnology, Faculty of Biotechnology, University of Sadat City, Sadat City, Egypt.
Manal A El-ShalDepartment of Microbiology, Faculty of Applied Health Sciences Technology, Horus University New Damietta, New Damietta, Egypt.
Eman FikryPharmacognosy Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Rawia A ZayedPharmacognosy Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Wafaa M IsmaeilPharmacognosy Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antibiotic resistance of pathogenic microorganisms due to the irresponsible use in healthcare and agricultural practices is one of the global threats for the human, especially immune-compromised patients. Thus, searching for a novel compounds from fungi with unique affinity to combat the drug-resistant microorganisms was the objective. Talaromyces purpurogenus # PZ292970.1, an endophyte of palm tree Elaeis guineensis, has the highest productivity of azaphilone pigment (25.5 AU410/ml), with a strong activity against E. coli (MIC value 6.8 µg/ml), S. aureus and C. albicans (MIC value 12.5 µg/ml). The extracted pigment of T. purpurogenus has a strong antibiofilm activity for S. aureus (86.2%), C. albicans (85.8%) and E. coli (79.7%), compared to the control. The TLC purified-pigment of T. purpurogenus had a maximum absorbance at λ

Indexed as

Anti-Infective AgentsAntioxidantsBenzopyransPigments, BiologicalTalaromycesBiofilmsCandida albicansEscherichia coliMicrobial Sensitivity TestsMolecular Docking SimulationStaphylococcus aureusAnti-Infective AgentsAntioxidantsazaphiloneBenzopyransPigments, BiologicalAntimicrobial activityDihydromonascorubrinPigmentsTalaromyces purpurogenusγ- irradiation

Identifiers

PMID42907759
PMCPMC13688843

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.