ReviewAdvances in experimental medicine and biology2026
Analytical Insights into Biologically Active Substances Using Mass Spectrometric Techniques.
Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
7 authors.
Funding
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Abstract
Currently, research on biologically active substances with therapeutic properties is advancing along two main directions. Firstly, considerable efforts are being devoted to reducing side effects by incorporating these drugs into various matrices that play an essential role in controlled drug delivery and release. On the other hand, new compounds derived from existing active substances are being synthesized-compounds that are cheaper to obtain, display fewer adverse reactions, and simultaneously match the therapeutic efficacy of the drugs from which they originate. Moreover, one of the most effective techniques for analyzing these compounds continues to be HPLC-MS. Its high sensitivity for detecting extremely low concentrations (on the order of ng/mL), together with its precision, accuracy, reproducibility, and reasonable operating cost, makes HPLC--MS an indispensable tool in any research laboratory. This review aims to summarize recent advances in HPLC-MS methods for the detection and quantification of three classes of therapeutic substances (anti-inflammatory, anti-diabetic, and anti-cancer drugs) and to provide perspectives on their applications in pharmacokinetic studies, quality control, and drug metabolism research.
Indexed as
Identifiers
42907644What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.