Evidence map›Paper›PMID 42907503›Full record

ArticleNature2026

GRP75-dependent SIMPA mediates inter-organellar quality control.

Fan Yu, Lingyu Jiang, Hanyu Liu, Song Yang, Yuan Yuan, Hongzhen Jin, Jinming Liu, Xi Liu, Yu Dong, Dongfeng Ren and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Fan Yu *The State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China. yufan@uhrs.edu.cn.ORCID http://orcid.org/0009-0006-7584-8593
Lingyu Jiang *The State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China.
Hanyu LiuThe State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China.
Song YangQingdao Central Hospital, NHC Key Laboratory of Cardiopulmonary Rehabilitation and Functional Recovery, Industry-Academia-Research Collaborative and Innovation Center for Intelligent Rehabilitation Drug R&D of Shandong Province, Qingdao Key Laboratory of Precision Drug Research for Chronic Disease Rehabilitation, University of Health and Rehabilitation Sciences, Qingdao, China.
Yuan YuanAier Academy of Ophthalmology, Central South University, Tianxin District, Changsha, China.
Hongzhen JinQingdao Central Hospital, NHC Key Laboratory of Cardiopulmonary Rehabilitation and Functional Recovery, Industry-Academia-Research Collaborative and Innovation Center for Intelligent Rehabilitation Drug R&D of Shandong Province, Qingdao Key Laboratory of Precision Drug Research for Chronic Disease Rehabilitation, University of Health and Rehabilitation Sciences, Qingdao, China.
Jinming LiuThe State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China.
Xi LiuThe State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China.
Yu DongThe State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China.
Dongfeng RenThe State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China.
Jie KangQingdao Central Hospital, NHC Key Laboratory of Cardiopulmonary Rehabilitation and Functional Recovery, Industry-Academia-Research Collaborative and Innovation Center for Intelligent Rehabilitation Drug R&D of Shandong Province, Qingdao Key Laboratory of Precision Drug Research for Chronic Disease Rehabilitation, University of Health and Rehabilitation Sciences, Qingdao, China.
Yan HuangThe State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China.
Qi MengThe State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China.
Feng BaiThe State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China.
Yanjun LiThe State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China.ORCID http://orcid.org/0000-0003-3199-8670
Shuoguo LiInstitute of Biophysics, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-3471-1316
Huadong LiuQingdao Central Hospital, NHC Key Laboratory of Cardiopulmonary Rehabilitation and Functional Recovery, Industry-Academia-Research Collaborative and Innovation Center for Intelligent Rehabilitation Drug R&D of Shandong Province, Qingdao Key Laboratory of Precision Drug Research for Chronic Disease Rehabilitation, University of Health and Rehabilitation Sciences, Qingdao, China.
Wei ZhaoQingdao Central Hospital, NHC Key Laboratory of Cardiopulmonary Rehabilitation and Functional Recovery, Industry-Academia-Research Collaborative and Innovation Center for Intelligent Rehabilitation Drug R&D of Shandong Province, Qingdao Key Laboratory of Precision Drug Research for Chronic Disease Rehabilitation, University of Health and Rehabilitation Sciences, Qingdao, China.
Jia XiaoQingdao Central Hospital, NHC Key Laboratory of Cardiopulmonary Rehabilitation and Functional Recovery, Industry-Academia-Research Collaborative and Innovation Center for Intelligent Rehabilitation Drug R&D of Shandong Province, Qingdao Key Laboratory of Precision Drug Research for Chronic Disease Rehabilitation, University of Health and Rehabilitation Sciences, Qingdao, China. edwinsiu@connect.hku.hk.ORCID http://orcid.org/0000-0001-5647-4190
Quan ChenThe State Key Laboratory of Medicinal Chemical Biology and Frontier of Science Center for Cell Response, College of Life Sciences, Nankai University, Tianjin, China. chenq@nankai.edu.cn.ORCID http://orcid.org/0000-0001-7539-8728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are bound by a double membrane and are semiautonomous organelles, rendering them highly vulnerable to global and internal proteostatic stress

Identifiers

PMID42907503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.