Evidence map›Paper›PMID 42907495›Full record

ArticleNature metabolism2026

A futile Na

Qing Liu, Ying Cheng, Dandan Yan, Wenjie Wu, Zhenchuan Lei, Qiaoyun Long, Ziyu Zhao, Yuan Gao, Baile Wang, Tianshi Feng and 21 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Qing LiuState Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.
Ying ChengState Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.
Dandan YanState Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Centre for Diabetes, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wenjie WuSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Zhenchuan LeiSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Qiaoyun LongSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Ziyu ZhaoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Yuan GaoState Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.
Baile WangState Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.
Tianshi FengState Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.
Jihoon ShinDivision of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA.
Jiayu ZhaoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Shiting ZhaoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Kang ChenState Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.
Kingyip ChengDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Xiaoqiang YaoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Ping GuDepartment of Endocrinology, Jinling Hospital, Nanjing University, Nanjing, China.
Xuefei GaoDepartment of Physiology, Southern Medical University, Guangzhou, China.
Ching-Lung CheungDepartment of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0002-6233-9144
Shingo KajimuraDivision of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0672-5910
Pengtao LiuStem Cell and Regenerative Medicine Consortium, Li Ka Shing Faculty of Medicine, School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
Donghai WuChina-New Zealand Joint Laboratory on Biomedicine and Health, Guangdong Provincial Key, Laboratory of Stem Cell and Regenerative Medicine, Institute of Development and Regeneration, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Wei SunChina-New Zealand Joint Laboratory on Biomedicine and Health, Guangdong Provincial Key, Laboratory of Stem Cell and Regenerative Medicine, Institute of Development and Regeneration, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Jinfeng XiaoChina-New Zealand Joint Laboratory on Biomedicine and Health, Guangdong Provincial Key, Laboratory of Stem Cell and Regenerative Medicine, Institute of Development and Regeneration, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Zexin LinChina-New Zealand Joint Laboratory on Biomedicine and Health, Guangdong Provincial Key, Laboratory of Stem Cell and Regenerative Medicine, Institute of Development and Regeneration, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.ORCID http://orcid.org/0000-0003-4091-6809
Yi WangDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Maxwell KwokSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0001-5920-9341
Ngar Yun Ellen PoonSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0002-9280-3681
Cheng HuState Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Centre for Diabetes, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0003-4314-2386
Aimin XuState Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0002-0668-033X
Hannah Xiaoyan HuiState Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong, China. hannahhui@cuhk.edu.hk.ORCID http://orcid.org/0000-0002-7525-5812

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82325010
6 · The paper itself

Abstract

Uncoupling protein 1 (UCP1)-independent energy dissipation has been proven to serve physiological functions in beige adipocytes. Here we show that a futile sodium/potassium (Na

Identifiers

PMID42907495

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.