Evidence map›Paper›PMID 42905940›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2026

NSG Mice Lacking Apoe: An Immunodeficient Mouse Model of Atherosclerosis.

Hannah R Megathlin, Lisa Burzenski, David A Coleman, Blaze Albert, Michelle L Farley, Michael A Brehm, Dale L Greiner, Leonard D Shultz

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hannah R MegathlinThe Jackson Laboratory, Bar Harbor, Maine, USA.ORCID https://orcid.org/0000-0002-8934-7654
Lisa BurzenskiThe Jackson Laboratory, Bar Harbor, Maine, USA.ORCID https://orcid.org/0000-0002-7767-2345
David A ColemanThe Jackson Laboratory, Bar Harbor, Maine, USA.ORCID https://orcid.org/0009-0000-6459-8599
Blaze AlbertThe Jackson Laboratory, Bar Harbor, Maine, USA.ORCID https://orcid.org/0009-0006-5113-5417
Michelle L FarleyThe Jackson Laboratory, Bar Harbor, Maine, USA.ORCID https://orcid.org/0009-0001-1376-8495
Michael A BrehmProgram in Molecular Medicine, Diabetes Center of Excellence, UMass Chan Medical School, Worcester, Massachusetts, USA.ORCID https://orcid.org/0000-0001-6813-3262
Dale L GreinerProgram in Molecular Medicine, Diabetes Center of Excellence, UMass Chan Medical School, Worcester, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5923-339X
Leonard D ShultzThe Jackson Laboratory, Bar Harbor, Maine, USA.ORCID https://orcid.org/0000-0002-4868-1031

Funding

Models to study the synergy between autoimmunity and metabolism in T1DUG3DK142192 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Michael Allen Brehm, George Q Daley · 2025 to 2026
$2.4M
Breakthrough T1D (JDF) 4-COE-2025-1751-A-NHHS | NIH | National Institute of General Medical Sciences (NIGMS) 3T32GM132006HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM) UG3 DK142192Jackson Laboratory (JAX)
6 · The paper itself

Abstract

Murine research on atherosclerosis has been conducted largely on the C57BL/6 (B6) strain background, and most commonly, the B6.129P2-Apoe

Indexed as

Apolipoproteins EAtherosclerosisDisease Models, AnimalAnimalsDiet, High-FatFemaleHumansMiceMice, Inbred NODMice, KnockoutMice, Knockout, ApoEApolipoproteins EApolipoproteins Eatherosclerosishumanshypercholesterolemiaimmune systeminbred NODmice

Identifiers

PMID42905940
PMCPMC13686551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.