ReviewEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2026
The future of PFA in cardiac ablation procedures.
Review in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Pulsed field ablation (PFA) has rapidly emerged as a major development in catheter ablation, with increasing clinical adoption driven by procedural efficiency and a favorable safety profile compared with thermal energies. This article summarizes the future directions of PFA in electrophysiology, focusing on technological innovation, and how these advances are expected to expand PFA clinical indications. Additionally, this article provides a perspective on current gaps and future challenges of PFA. A perspective on future developments in new waveforms, catheter architectures, and integration with electroanatomical mapping systems for PFA is summarized. The document discusses novel waveform configurations and catheter design concepts that may improve lesion quality, procedural versatility, and safety. Additionally, this article also reviews how parallel advances in electroanatomical mapping integration, artificial intelligence, and robotic navigation are expected to enhance procedural guidance and enable individualized therapy. This manuscript summarizes the potential applications of PFA beyond pulmonary vein isolation and how emerging evidence supports its feasibility for linear atrial lesions, substrate modification, treatment of complex atrial tachycardias, and ventricular arrhythmia ablation. In addition, this article provides insights on how PFA may facilitate catheter ablation in new patient populations including elderly patients and those with higher procedural risks. Finally, this manuscript provides an outlook at major remaining challenges and knowledge gaps for PFA. The lack of homogenous procedural endpoints definitions and lesion durability assessment are discussed. Furthermore, this article highlights the need for standardized terminology and reporting in an environment where the high heterogeneity between available commercial systems complicates comparison across technologies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.