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ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2026

Development of an artificial intelligence algorithm for automated detection of cardiovascular intervention-related complications.

Arnoud Okken, Rob Wanders, Andre Klappe, Kasper F Beukema, Tom Oirbans, Peter G Noordzij, Anouk van Lent, Saskia H Haanemaaier, Jippe C Balt

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Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. AI in daily cardiology and structured multidisciplinary care.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Arnoud OkkenDepartment of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
Rob WandersParnas, IT-Services and Consultancy, Groningen, The Netherlands.
Andre KlappeParnas, IT-Services and Consultancy, Groningen, The Netherlands.
Kasper F BeukemaDepartment of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
Tom OirbansDepartment of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
Peter G NoordzijDepartment of Anesthesiology and Intensive Care Medicine, St. Antonius Hospital, Nieuwegein, The Netherlands.
Anouk van LentDepartment of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
Saskia H HaanemaaierDepartment of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
Jippe C BaltDepartment of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands. j.balt@antoniusziekenhuis.nl.ORCID http://orcid.org/0000-0002-7880-3730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntervention-related complications negatively affect healthcare quality and costs. Complication registration and reporting play an important role in the improvement of healthcare outcomes but are time-consuming and hampered by under-reporting.

methodsWe developed an artificial intelligence (AI)-aided tool that extracts specific complications, including bleeding, tamponade, CVA and phrenic paralysis, from electronic healthcare records of patients undergoing pulmonary vein isolation (PVI), percutaneous transluminal coronary angioplasty (PTCA) and transcatheter aortic valve implantation (TAVI). Both structured and unstructured data were used, along with additional signals identified through machine learning. The model was optimized to achieve high sensitivity.

resultsElectronic records of 6,564 patients undergoing PVI, PTCA, and TAVI, performed at our hospital from 2017-2022, were used. The final model detected the various complications with a sensitivity between 94.4 and 100%, while specificity ranged from 99.4-100%. This resulted in positive predictive values ranging from 47.5-81%, with F‑scores varying between 0.64-0.87.

conclusionWe developed an AI-driven tool capable of automatically detecting complications following cardiac interventions from patient healthcare records, achieving a very high sensitivity. Our tool enables registration of complications while significantly reducing administrative burden on the healthcare providers and data managers. It provides valuable and high-quality input for improvement cycles, thereby enhancing patient safety and healthcare quality.

Indexed as

Artificial intelligenceCardiovascular interventionComplication registrationElectronic patient recordNatural language processing

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.