ArticleInternational ophthalmology2026
Long-term evaluation of anterior segment structures after implantable collamer lens V4c implantation.
Article in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate the long-term outcomes of anterior segment parameters following implantable collamer lens (ICL V4c) implantation in highly myopic patients.
settingA tertiary specialized eye hospital in Shanghai, China.
designProspective, non-randomized, consecutive case series.
methodsThis study included 32 eyes of 20 patients with high myopia who underwent ICL V4c implantation with a 3-year follow-up. Preoperative assessments included standard biometry and anterior segment parameters. Postoperative evaluations were conducted at 1 day, 1 month, 3 months, and 3 years. Parameters assessed included corneal endothelium-anterior capsule distance (ACD-L), corneal endothelium-ICL distance (ACD-ICL), ICL-anterior capsule distance (ICL-L), anterior chamber angle (ACA) parameters, and iris metrics.
resultsACD-L decreased significantly postoperatively from baseline to 1 day (P < 0.001) but remained stable thereafter (e.g.,P = 0.397 between 1 day and 3 years). ACD-ICL increased over time, while ICL-L (vault) decreased significantly (P < 0.001), with the most pronounced changes occurring in the first month. All ACA parameters (ACW, AOD500, ARA500, TISA500, TIA500) decreased significantly compared to preoperative values (all P < 0.001) but showed no significant differences among postoperative follow-up points. Iris area (IA) and iris volume (IV) showed transient changes at 1 day post-surgery but returned to baseline levels thereafter (P = 0.302 for IA and P = 0.330 for IV at 3 years versus baseline).
conclusionsDuring the 3-year follow-up of ICL V4c implantation, a gradual increase in ACD-ICL was significantly associated with vault reduction.
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