ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2026
From Corneal Epithelium to Endothelium: Long-Term Corneal Changes in Myopic Children Wearing Daily Disposable Hydrogel Soft Contact Lenses.
Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aims to investigate the long-term impact of soft contact lens (SCL) wear on the cornea in children.
methodsTwenty-one participants who had worn daily disposable hydrogel SCLs for over 10 years (≥10 h/day, 6 days/week) since ages 8-12 years were recruited, together with age-matched controls without contact lens wear. Corneal epithelial (CET) and stromal thickness (CST) were measured using anterior segment optical coherence tomography in central (2 mm), mid-peripheral (2-5 mm) and peripheral (5-6 mm) annular regions. Corneal endothelium was imaged with a non-contact specular microscope to calculate corneal endothelial cell density (ECD), coefficients of variation of cell size (polymegethism, CV,%) and percentage of hexagonal cells (pleomorphism, HEX,%) in the central and six peripheral regions.
resultsParticipants' mean age was 21.3 ± 1.2 years in the control group (12 females) and 21.6 ± 1.5 years in the SCL group (10 females). Mean central 2-mm CET and CST were similar between groups (CET: Control vs SCL: 52.4 ± 3.4 vs 52.2 ± 2.5 μm, CST: 478.3 ± 30.8 vs 487.6 ± 23.4, both p > 0.20), with no significant differences in peripheral regions (p > 0.10). Neither central ECD (3064 ± 249 vs 3076 ± 203 cells/mm
conclusionLong-term wear of daily disposable hydrogel SCLs in children did not alter CET and CST significantly over a minimum 10-year period. Corneal endothelial integrity and pleomorphism were maintained, with higher polymegethism observed only in two peripheral regions. These findings support daily disposable hydrogel SCLs as a safe and suitable choice for children over a typical myopia control treatment period.
Indexed as
Identifiers
42905236What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.