Evidence map›Paper›PMID 42905218›Full record

ArticleJournal of echocardiography2026

Echocardiographic predictors of left ventricular ejection fraction improvement after transcatheter aortic valve replacement.

Shin Sato, Akiko Kumagai, Kai Ninomiya, Akiko Murofushi, Kaho Shimada, Michiko Yoshizawa, Ryo Ninomiya, Tetsuya Fusazaki, Yoshihiro Morino

Abstract read
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Article in Journal of echocardiography, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shin SatoDivision of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba, Iwate, Japan.
Akiko KumagaiDivision of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba, Iwate, Japan. akumagai@iwate-med.ac.jp.ORCID http://orcid.org/0000-0003-0436-1957
Kai NinomiyaDivision of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba, Iwate, Japan.
Akiko MurofushiDivision of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba, Iwate, Japan.
Kaho ShimadaDivision of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba, Iwate, Japan.
Michiko YoshizawaDivision of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba, Iwate, Japan.
Ryo NinomiyaDivision of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba, Iwate, Japan.
Tetsuya FusazakiDivision of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba, Iwate, Japan.
Yoshihiro MorinoDivision of Cardiology, Department of Internal Medicine, Iwate Medical University, 2-1-1 Idaidori, Yahaba, Iwate, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImprovement in left ventricular ejection fraction (LVEF) after transcatheter aortic valve replacement (TAVR) has been associated with better clinical outcomes, but predictors of recovery remain poorly defined. This study aimed to identify echocardiographic parameters associated with post-TAVR LVEF improvement in patients with severe aortic stenosis (AS) and reduced LVEF.

methodsAmong 1,133 consecutive patients who underwent TAVR between December 2013 and June 2024, 128 with baseline LVEF < 50% and follow-up echocardiography within 3 months were analyzed. LVEF improvement was defined as an absolute increase ≥ 10%. Independent predictors were identified using multivariable logistic regression. Post-procedural outcomes were assessed using Kaplan-Meier analysis.

resultsLVEF improvement occurred in 64 patients (50%). Multivariable analysis identified higher left ventricular mass index (LVMI) (OR 1.02, 95% CI 1.00-1.03, P = 0.01) and higher E/e' (OR 1.10, 95% CI 1.03-1.18, P < 0.01) as independent predictors of improvement, whereas larger left ventricular end-diastolic volume (LVEDV) (OR 0.98, P = 0.01) and larger AVA (OR 0.67 per 0.1 cm², P < 0.01) were inversely associated. Patients with LVEF improvement had significantly lower 1-year all-cause mortality (98.2% vs. 87.0%, P = 0.01).

conclusionsEchocardiographic parameters reflecting pressure overload and diastolic dysfunction predict LVEF recovery after TAVR. Postoperative LVEF improvement was associated with better 1-year survival, underscoring its prognostic value.

Indexed as

Aortic stenosisEchocardiographyLeft ventricular ejection fractionReverse remodelingTranscatheter aortic valve replacement

Identifiers

PMID42905218

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.