ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026
Three-year cohort study on the predictive role of axial length-to-corneal radius ratio in the incidence and progression of myopia among Chinese schoolchildren.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo explore the role of axial length/corneal radius (AL/CR) ratio both in the incidence and progression of myopia among a 3-year cohort of school children.
methodsThe baseline survey was conducted in 2020 to collect basic information by a questionnaire and perform an ophthalmological examination. Subsequent follow-up examinations were conducted annually for three years. Cycloplegic refraction was used to measure the spherical equivalent (SE), and IOL Master was used to measure axial length (AL) and corneal radius (CR). AL/CR ratio was calculated.
resultsA total of 1521 students were included in the analysis. Myopia prevalence was 19.9% at baseline, and the 3-year cumulative incidence and relatively rapid progression rates were 54.2% and 23.4%, respectively. Regression model showed that the 3-year incidence rate of myopia for those with an AL/CR ratio of 3.0 or higher was 1.95 times that for those below 3.0 (P < 0.001), after adjusting for confounding factors. Model comparisons revealed that the AL/CR ratio was particularly predictive for the onset of myopia in nonmyopic individuals, especially in those with an AL/CR ratio below 3.0.
conclusionsThe AL/CR ratio demonstrated incremental predictive power for the incidence of myopia over a 3-year period in non-myopic schoolchildren particularly in those with ratios below 3.0. These findings support shifting from binary screening to continuous risk stratification across the full AL/CR spectrum.
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