Evidence map›Paper›PMID 42905156›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Suicide mortality among survivors of first primary thyroid cancer: a population-based competing risk analysis.

Endong Chen, Tao Zhang, Zizhou Huang, Jing Lin, Qianqing Ji, Chen Chen, Yingying Chen, Jiayi Zhang, Zhenxuan Huang, Weiyi Wang and 5 more

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Endong Chen *Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Tao Zhang *Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zizhou Huang *The First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jing Lin *Department of Obstetrics and Gynecology, The First People's Hospital of Longwan District, Wenzhou, Zhejiang, China.
Qianqing JiDepartment of Cellular and Molecular Anatomy, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-Ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Chen ChenDepartment of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Yingying ChenDepartment of Colorectal and Anal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jiayi ZhangThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhenxuan HuangThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Weiyi WangThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Qingru HuaThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Tianlang WengThe First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Qingxuan WangDepartment of Thyroid Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yefeng CaiDepartment of Thyroid Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Jie YouDepartment of Thyroid Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. Youjie_123@hotmail.com.

Funding

double training project of the First Affiliated Hospital of Wenzhou Medical University spy202114Science and Technology Plan Project of Wenzhou Y2023156; Y20240042
6 · The paper itself

Abstract

introductionThyroid cancer is associated with favorable survival, yet suicide risk during long-term survivorship remains incompletely characterized, particularly in the presence of competing mortality.

methodsWe identified 178,014 patients with first primary thyroid cancer from the SEER 17 database between 2000 and 2022. Suicide mortality was quantified using standardized mortality ratios. Risk factors were evaluated using cause-specific Cox models and Fine-Gray competing risk regression, with non-suicide deaths treated as competing events.

resultsDuring 1,566,507 person-years of follow-up, 165 suicides occurred, corresponding to 10.53 deaths per 100,000 person-years. Overall suicide mortality was comparable to that of the general population. In cause-specific Cox models, older age, no surgery, and chemotherapy appeared associated with suicide risk. These associations did not reach statistical significance in the Fine-Gray model. Male sex, single status, and separated/divorced status remained independently associated with higher suicide incidence, whereas the highest area-level median household income category was associated with lower suicide incidence.

conclusionSociodemographic factors were associated with suicide incidence in the Fine-Gray model, supporting attention to psychosocial vulnerability alongside disease-related needs. These findings support incorporating social vulnerability assessment, psychosocial screening, and referral pathways into supportive care for patients with thyroid cancer.

Indexed as

Cancer SurvivorsSuicideThyroid NeoplasmsAdultAgedAge FactorsFemaleHumansIncidenceMaleMiddle AgedProportional Hazards ModelsRisk AssessmentRisk FactorsSEER ProgramSex FactorsPsycho-OncologySuicideSupportive careSurveillance, Epidemiology, and End Results (SEER) programThyroid cancer

Identifiers

PMID42905156

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