Evidence map›Paper›PMID 42904998›Full record

ArticleJournal of agricultural and food chemistry2026

Size-Dependent Zinc Delivery and Nanozyme-Mediated Stress Alleviation by ZnO Nanoparticles in Zinc-Deficient Tomato.

Selahattin Kondak, Dóra Kondak, Tamás Bodor, Gábor Fejes, Attila Ördög, Andrea Rónavári, Zoltán Kónya, Réka Szőllősi, András Kukri, Attila Gyenesei and 12 more

Abstract read
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In one paragraph

Article in Journal of agricultural and food chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Selahattin KondakDepartment of Plant Biology, University of Szeged, Szeged6726, Hungary.ORCID 0000-0003-4979-5986
Dóra KondakDepartment of Plant Biology, University of Szeged, Szeged6726, Hungary.
Tamás BodorDepartment of Plant Biology, University of Szeged, Szeged6726, Hungary.
Gábor FejesDepartment of Plant Biology, University of Szeged, Szeged6726, Hungary.
Attila ÖrdögDepartment of Plant Biology, University of Szeged, Szeged6726, Hungary.
Andrea RónaváriDepartment of Applied and Environmental Chemistry, University of Szeged, Szeged6720, Hungary.ORCID 0000-0001-7054-0975
Zoltán KónyaDepartment of Applied and Environmental Chemistry, University of Szeged, Szeged6720, Hungary.ORCID 0000-0002-9406-8596
Réka SzőllősiDepartment of Plant Biology, University of Szeged, Szeged6726, Hungary.
András KukriDepartment of Plant Biology, University of Szeged, Szeged6726, Hungary.
Attila GyeneseiHungarian Centre for Genomics and Bioinformatics, Szentágothai Research Centre, University of Pécs, Pécs7624, Hungary.
Péter UrbánHungarian Centre for Genomics and Bioinformatics, Szentágothai Research Centre, University of Pécs, Pécs7624, Hungary.
József KunHungarian Centre for Genomics and Bioinformatics, Szentágothai Research Centre, University of Pécs, Pécs7624, Hungary.
Maria GrachevaBudapest Neutron Centre, Institute for Energy Security and Environmental Safety, HUN-REN Centre for Energy Research, Budapest1121, Hungary.
Ádám SoltiDepartment of Plant Physiology and Molecular Plant Biology, Institute of Biology, ELTE Eötvös Loránd University, Budapest1117, Hungary.
Kinga BenczúrAgricultural Institute, HUN-REN Centre for Agricultural Research, Martonvásár2462, Hungary.
Magda PálAgricultural Institute, HUN-REN Centre for Agricultural Research, Martonvásár2462, Hungary.ORCID 0000-0003-3468-962X
Gabriella SzalaiAgricultural Institute, HUN-REN Centre for Agricultural Research, Martonvásár2462, Hungary.
Ildikó DomonkosInstitute of Plant Biology, HUN-REN Biological Research Centre, Szeged6726, Hungary.
Titanilla SzögiDepartment of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged6720, Hungary.
Fernando A Casian PlazaDepartment of Molecular and Analytical Chemistry, University of Szeged, Szeged6720, Hungary.
Gábor GalbácsDepartment of Molecular and Analytical Chemistry, University of Szeged, Szeged6720, Hungary.ORCID 0000-0002-1799-5329
Zsuzsanna KolbertDepartment of Plant Biology, University of Szeged, Szeged6726, Hungary.ORCID 0000-0002-7819-4672

Funding

Magyar Tudom??nyos Akad??mia LENDULET_2023-40National Research, Development and Innovation Office K 135303National Research, Development and Innovation Office K 146733
6 · The paper itself

Abstract

Zinc (Zn) deficiency severely limits plant growth and yield, highlighting the need for strategies to improve Zn nutrition. Here, Zn oxide nanoparticles (nZnOs) of two sizes (∼8 nm and ∼45 nm, 100 mg·L-1) were evaluated as seed priming agents in tomato grown under Zn-deficient conditions. Both nanoparticle sizes were internalized into embryonic tissues and showed distinct intracellular localization. While 45 nm nZnO and bulk Zn disturbed seed nutrient homeostasis, 8 nm nZnO increased seed Zn content more efficiently, with milder effects on other nutrients. Across developmental stages, nZnO priming improved Zn supply and nutrient distribution more effectively than bulk Zn. At the vegetative stage, 45 nm nZnO enhanced overall biomass, whereas 8 nm nZnO promoted root-specific growth under Zn deficiency. nZnO priming increased root Zn accumulation, particularly with 8 nm nZnO, and alleviated Zn deficiency-induced nonspecific metal accumulation. Zn deficiency-induced disturbances in redox and nitrosative balance were reversed by nZnO priming, accompanied by reduced RNA nitration and a shift toward a catalase-dominated hydrogen peroxide detoxification system. Both nanoparticle sizes exhibited peroxidase-like activity in cell-free assays, indicating nanozyme potential; however, this activity did not translate directly to the in planta responses. Under Zn deficiency, nZnO priming suppressed stress-related metabolic pathways in leaves, while enhancing amino acid, polyamine, and structural carbohydrate metabolism in roots. Zn deficiency-induced transcriptional repression, particularly in leaves, was partially restored, with affected genes enriched in stress-, phytohormone-, and detoxification-related pathways. Overall, size-dependent nZnO seed priming alleviates Zn deficiency in tomato. 45 nm nZnO mainly enhances biomass through improved nutrient homeostasis and redox regulation, while both sizes contribute to restored Zn availability and antioxidant reprogramming under Zn deficiency.

Indexed as

NanoparticlesSolanum lycopersicumZincZinc OxideMetal NanoparticlesParticle SizePlant ProteinsPlant RootsSeedsStress, PhysiologicalPlant ProteinsZincZinc Oxidemetabolomicsnanozymeseed primingsuboptimal zinc supplytranscriptomicszinc oxide nanoparticles

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.