Evidence map›Paper›PMID 42904831›Full record

ReviewPain research & management2026

Beyond the Ladder: A 10-Domain Cognitive and Operational Toolkit to Humanise and Implement Acute Pain Guidelines at the Bedside.

Michele Domenico Spampinato, Sossio Serra, Alessandro Riccardi, Mario Guarino, Claudia Sara Cimmino, Enrico Gandolfo, Fabio De Iaco

Abstract readReview
In one paragraph

Review in Pain research & management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michele Domenico SpampinatoNational Study Group on Pain Management and Procedural Sedation and Analgesia (SAU Group), Italian Society of Emergency Medicine (SIMEU), Turin, Italy.ORCID https://orcid.org/0000-0002-2285-327X
Sossio SerraNational Study Group on Pain Management and Procedural Sedation and Analgesia (SAU Group), Italian Society of Emergency Medicine (SIMEU), Turin, Italy.ORCID https://orcid.org/0000-0002-9281-3601
Alessandro RiccardiNational Study Group on Pain Management and Procedural Sedation and Analgesia (SAU Group), Italian Society of Emergency Medicine (SIMEU), Turin, Italy.ORCID https://orcid.org/0000-0002-4936-1531
Mario GuarinoNational Study Group on Pain Management and Procedural Sedation and Analgesia (SAU Group), Italian Society of Emergency Medicine (SIMEU), Turin, Italy.
Claudia Sara CimminoNational Study Group on Pain Management and Procedural Sedation and Analgesia (SAU Group), Italian Society of Emergency Medicine (SIMEU), Turin, Italy.
Enrico GandolfoNational Study Group on Pain Management and Procedural Sedation and Analgesia (SAU Group), Italian Society of Emergency Medicine (SIMEU), Turin, Italy.
Fabio De IacoNational Study Group on Pain Management and Procedural Sedation and Analgesia (SAU Group), Italian Society of Emergency Medicine (SIMEU), Turin, Italy.ORCID https://orcid.org/0009-0001-1155-4792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough pain is among the most common reasons for emergency department (ED) attendance, oligoanalgesia remains a persistent global issue. While the 2026 EUSEM guidelines provide evidence-based pharmacological recommendations, translating these into the crowded ED environment is often constrained by systemic overcrowding and a traditional reliance on technical skills, with limited integration of human factors and nontechnical skills relevant to suffering. The objective of this position paper is to propose a practical, human-centred operational framework that bridges scientific guidelines with clinical realities. DISCUSSION: The resulting 10-domain cognitive and operational toolkit synthesises technical and nontechnical skills without implying a mandatory sequence. The domains comprise: (1) establishing psychological safety and therapeutic engagement; (2) multidimensional assessment, including potential indicators of pain and selective neuropathic screening; (3) shared goals and care planning; (4) context-triggered caregiver integration; (5) severity-matched, mechanism-informed multimodal analgesia; (6) individualised opioid stewardship for opioid exposure, tolerance and Opioid Use Disorder; (7) an independent palliative and end-of-life domain, including proportional palliative sedation only for appropriately assessed refractory suffering; (8) contextual assessment of broader palliative and social needs; (9) anticipatory workflow, reassessment and rescue planning and (10) handoff and continuity of care. Domains 1, 2, 3, 5, 9 and 10 are core; domains 4, 6, 7 and 8 are context-triggered. All 10 are briefly considered, while specific tools and actions are activated only when clinically relevant. PERSPECTIVE: This position paper addresses the persistent gap between evidence-based guidelines and the operational realities of overcrowded EDs. By integrating pharmacology with essential nontechnical skills, the proposed 10-domain toolkit provides a human-centred cognitive and operational model for daily clinical practice. It is nonsequential: all domains are briefly considered, while core and context-triggered actions are activated according to clinical relevance. The model requires local adaptation and prospective evaluation.

conclusionsEffective pain management is an ethical imperative that requires both pharmacological competence and nontechnical skills. This framework serves as a cultural, cognitive and operational guide, helping clinicians embed proactive, individualised pain relief, reassessment and continuity into the demanding workflow of the modern ED. As an expert-informed toolkit rather than a validated pathway, it requires local adaptation and prospective evaluation.

Indexed as

Acute PainPain ManagementPractice Guidelines as TopicHumansdecision-makingemergency medicinemultimodal analgesiapain managementpalliative care

Identifiers

PMID42904831
PMCPMC13685511

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.