Apalutamide-induced drug reaction with eosinophilia and systemic symptoms and Stevens-Johnson syndrome overlap successfully treated with cyclosporine and benralizumab: A case report and literature review.

Alaa Erras, Zachary J Jaeger, Lena Chu, Helen H Park, Brian R Hinds, Reid Oldenburg

Abstract readCase Reports

In one paragraph

Article in JAAD case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alaa ErrasDepartment of Dermatology, University of California San Diego, School of Medicine, La Jolla, California.

Zachary J JaegerDepartment of Dermatology, University of California San Diego, School of Medicine, La Jolla, California.

Lena ChuDepartment of Dermatology, University of California San Diego, School of Medicine, La Jolla, California.

Helen H ParkDepartment of Dermatology, University of California San Diego, School of Medicine, La Jolla, California.

Brian R HindsDepartment of Dermatology, University of California San Diego, School of Medicine, La Jolla, California.

Reid OldenburgDepartment of Dermatology, University of California San Diego, School of Medicine, La Jolla, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

androgen receptor antagonistapalutamideARSIbenralizumabbullaCCL1CCL17CCR4CCR8corticosteroidsCsACXCL10CXCR3cyclosporin Acyclosporinedarolutamidedermal dendritic cellsdermatitisdesquamationDIHSDRESSDRESS-SJS overlapdrug-induced hypersensitivity syndromedrug reaction with eosinophilia and systemic symptomsenzalutamideeosinophiliaeosinophilserythrodermaexanthemIL-5 inhibitorimmunosuppressioninterfaceinterleukin-5JAK inhibitorJ-SCARkeratinocytesprostate cancerrashRegiSCARsevere cutaneous adverse reactionSJSSJS/TENStevens-Johnson syndromeTARCTENTh2toxic epidermal necrolysis

Identifiers

PMID42904225

DOI10.1016/j.jdcr.2026.08.045

PMCPMC13682493

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.