Evidence map›Paper›PMID 42904169›Full record

ArticleGut microbes reports2026

Halogenated flame retardant exposure was associated with pediatric gut microbiome profiles in a Canadian cohort.

Yidan Zhang, Feng Gao, Peng Gao, Yihan Fan, Xinlei Wang, Yuqiu Yang, Anthony Gagnon, Guillaume Martinez, Virginie Gillet, Jiping Zhu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yidan ZhangDepartment of Earth and Environmental Sciences, University of Texas at Arlington, Arlington, TX, USA.ORCID https://orcid.org/0009-0009-4165-7387
Feng GaoDepartment of Environmental Health Sciences, Fielding School of Public Health, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Peng GaoDepartment of Environmental Health and Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Yihan FanDepartment of Environmental Health Sciences, Fielding School of Public Health, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Xinlei WangDepartment of Mathematics, University of Texas at Arlington, Arlington, TX, USA.
Yuqiu YangQuantitative Biomedical Research Center, Department of Health Data Science and Biostatistics, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Anthony GagnonDépartement de Pédiatrie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC, Canada.
Guillaume MartinezDépartement de Chimie, Université de Sherbrooke, Sherbrooke, QC, Canada.
Virginie GilletDépartement de Pédiatrie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC, Canada.
Jiping ZhuEnvironmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada.
Jean-Philippe BellengerDépartement de Chimie, Université de Sherbrooke, Sherbrooke, QC, Canada.
Andrea A BaccarelliDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Larissa TakserDépartement de Pédiatrie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC, Canada.
Yike ShenDepartment of Earth and Environmental Sciences, University of Texas at Arlington, Arlington, TX, USA.ORCID https://orcid.org/0000-0001-8480-8258

Funding

Effects of Flame Retardants on Brain Function and Attentional Deficits in School-age Children - Brain Imaging, Neurobehavioral, and Gut Microbiome Studies in a Longitudinal Birth CohortR01ES027845 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BACCARELLI, ANDREA, TAKSER, LARISSA · 2018 to 2022
$2.7M
NIEHS NIH HHS R01 ES027845
6 · The paper itself

Abstract

Environmental chemical exposures have been linked to gut microbiome dysregulation and adverse health outcomes in children. Halogenated flame retardants (HFRs) are persistent chemicals with substantial early-life exposure, yet evidence on their effects on the pediatric gut microbiome remains limited. We examined associations between HFR exposures and the gut microbiome among 8-12-y-old children from the GESTation and Environment (GESTE) cohort in Sherbrooke, Canada. In a multi-matrix, multi-omics design, 10 HFRs were quantified in plasma (

Indexed as

Halogenated flame retardantsmetagenomemetatranscriptomepediatric gut microbiome

Identifiers

PMID42904169
PMCPMC13682408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.