ArticleRespirology case reports2026
A Case of Platypnea-Orthodeoxia Syndrome Caused by Patent Foramen Ovale, Accompanied by Dilated Ascending Aorta, Thoracic Kyphosis and Persistent Eustachian Valve.
Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We present a case of platypnea-orthodeoxia syndrome (POS) associated with patent foramen ovale (PFO). In the upright position, right atrial compression resulting from a dilated ascending aorta and thoracic kyphosis modifies the spatial alignment of the PFO, orienting it toward inferior vena cava (IVC) inflow and increasing its tendency to remain patent. Further, a prominent Eustachian valve redirected blood returning from the IVC toward the PFO and thereby promoting right-to-left shunting. The patient subsequently underwent percutaneous transcatheter PFO closure. Even 10 months after the procedure, oxygen saturation measured on room air remained stable at 99% in both supine and upright positions.
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