Evidence map›Paper›PMID 42904116›Full record

ArticlePreventive medicine reports2026

Association between dual sensory impairments and new-onset cardiovascular disease among American middle-aged and older adults: the mediating role of depression.

Ziyan Lou, Xuan Chen, Xiaomin Wu, Xinze Han, Luhan Zhang, Chenyu Li, Jing Yuan, Fei Ma

Abstract read
In one paragraph

Article in Preventive medicine reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziyan LouDepartment of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
Xuan ChenDepartment of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
Xiaomin WuDepartment of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
Xinze HanDepartment of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
Luhan ZhangDepartment of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
Chenyu LiDepartment of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
Jing YuanDepartment of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
Fei MaDepartment of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to explore the association between dual sensory impairment (DSI) and incident cardiovascular disease (CVD), and to evaluate the potential mediating role of depression in this relationship. Methods: The data were sourced from 2017/2018 (Wave 14) to 2021/2022 (Wave 16) of the University of Michigan Health and Retirement Study (HRS) of the American aged 50 and above. A counterfactual-based causal mediation framework was employed to evaluate the mediating role of continuous depression scores in the association between DSI and new-onset CVD. Results: A total of 7582 participants were included, the incidence density of CVD is 23.67/1000 person-years. Compared with the people without VI (vision impairment) and HI (hearing impairment), those with DSI were associated with a significantly higher risk of CVD ( Conclusion: DSI was associated with a higher risk of CVD among middle-aged and older adults. The association was partially mediated by depression.

Indexed as

Cardiac eventsHearing impairmentMediation effectStrokeVision impairment

Identifiers

PMID42904116
PMCPMC13682056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.