Evidence map›Paper›PMID 42904076›Full record

ArticleCentral European journal of urology2026

Office-based transperineal laser ablation for benign prostatic hyperplasia: Functional outcomes and predictors of clinical improvement.

Juan Varela, Rafael Aldaya Bourricaudy, Evren Cekin, Brian Miles, Victoria Yvonne Bird

Abstract read
In one paragraph

Article in Central European journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juan VarelaUniversity of Florida College of Medicine, Gainesville, Florida, United States of America.
Rafael Aldaya BourricaudyUniversity of Florida College of Medicine, Gainesville, Florida, United States of America.
Evren CekinNational Medical Association and Research Group / Urologic Integrated Care, Gainesville, Florida, United States of America.
Brian MilesHouston Methodist Hospital, Houston, Texas, United States of America.
Victoria Yvonne BirdNational Medical Association and Research Group / Urologic Integrated Care, Gainesville, Florida, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Transperineal laser ablation (TPLA) is an ultrasound-guided, office-based procedure for the treatment of benign prostatic hyperplasia (BPH). This study evaluates short-term functional outcomes following TPLA and identifies predictors of clinical improvement. Material and methods: This cohort included men undergoing TPLA between January 1, 2025, and February 1, 2026, using a transperineal interstitial laser system (EchoLaser, Elesta SpA). Minimum follow-up was 6 months. Variables included age, body mass index (BMI), prostate-specific antigen (PSA), PSA density, testosterone, prostate volume, International Prostate Symptom Score (IPSS), peak urinary flow rate (Q Results: Thirty-five of forty men met the inclusion criteria. Mean prostate volume was 71.6 cm Conclusions: Office-based TPLA produced significant short term functional improvement. Functional gains were comparable to those achieved with hospital based surgical interventions. Prospective, multicenter, randomized studies are warranted to further evaluate long term durability.

Indexed as

benign prostatic hyperplasiaimage-guided surgeryminimally invasive therapyoffice-based urologytransperineal laser ablation

Identifiers

PMID42904076
PMCPMC13681842

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.