Evidence map›Paper›PMID 42903868›Full record

ArticlehLife2023

ppGpp is present in, and functions to regulate sleep of,

Xihuimin Dai, Wei Yang, Xiaohui Zhang, Enxing Zhou, Renbo Mao, Ying Liu, Tao Wang, Wenxia Zhang, Xinxiang Zhang, Yi Rao

Abstract read
In one paragraph

Article in hLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xihuimin DaiPeking-Tsinghua Center for Life Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University School of Life Sciences, and Chinese Institute for Brain Research, Beijing, China.
Wei YangPeking-Tsinghua Center for Life Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University School of Life Sciences, and Chinese Institute for Brain Research, Beijing, China.
Xiaohui ZhangState Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.
Enxing ZhouPeking-Tsinghua Center for Life Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University School of Life Sciences, and Chinese Institute for Brain Research, Beijing, China.
Renbo MaoPeking-Tsinghua Center for Life Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University School of Life Sciences, and Chinese Institute for Brain Research, Beijing, China.
Ying LiuState Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China.
Tao WangPeking-Tsinghua Center for Life Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University School of Life Sciences, and Chinese Institute for Brain Research, Beijing, China.
Wenxia ZhangPeking-Tsinghua Center for Life Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University School of Life Sciences, and Chinese Institute for Brain Research, Beijing, China.
Xinxiang ZhangCollege of Chemistry and Molecular Engineering, Peking University, Beijing, China.
Yi RaoPeking-Tsinghua Center for Life Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University School of Life Sciences, and Chinese Institute for Brain Research, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep is essential for animals, and receives inputs from circadian, homeostasis, and environment, yet the mechanisms of sleep regulation remain elusive. Discovery of molecules in living systems and demonstration of their functional roles are pivotal in furthering our understanding of the molecular basis of biology. Here, we report that guanosine-5'-diphosphate, 3'-diphosphate (ppGpp) is present in

Indexed as

DrosophilaMesh1ppGppsleepstarvation

Identifiers

PMID42903868
PMCPMC13681480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.