ArticleJournal of orthopaedic translation2026
PET/CT-guided navigation-assisted debridement for tibial fracture-related infection: a retrospective cohort study.
Article in Journal of orthopaedic translation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Fracture-related infection (FRI) is a serious complication secondary to fractures. Debridement plays a decisive role in the treatment of FRI, but precise debridement remains a surgical challenge. In this study, [ Methods: A retrospective analysis was conducted on patients with tibial FRI treated at our hospital between April 2021 and April 2024. A total of 78 patients were enrolled and divided into a navigation group (37 cases) and a conventional group (41 cases). Both groups underwent the two-stage Masquelet technique surgery. In the navigation group, the first-stage debridement of the infectious focus was performed under the full-process intelligent digital orthopedic operating system (Navi-OR 1) using preoperative [ Results: The navigation group had a significantly lower infection recurrence rate than the conventional group (10.8% [4/37] vs. 29.3% [12/41]; χ Conclusion: PET/CT-guided navigation-assisted debridement appears to be a feasible surgical approach for tibial FRI, with potential benefits in reducing infection recurrence and improving functional outcomes. However, further prospective multi-center studies with standardized protocols are warranted to confirm its clinical utility. The translational potential of this article: This study is the first to apply PET/CT-guided navigation-assisted debridement surgery for tibial FRI, in which preoperative PET/CT assists in delineating the suspected infectious focus and intraoperative real-time guidance with an optical navigation system enables accurate and complete debridement of the infected lesion, maximizes preservation of healthy tissue, and significantly reduces the infection recurrence rate.
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