Evidence map›Paper›PMID 42903678›Full record

ArticleMaterials today. Bio2026

Injectable self-healing polysaccharide hydrogel with slow-release b-FGF for adipose tissue regeneration.

Shuhan Wu, Wenjun Shu, Xulong Zhu, Yong Mei Chen, Zhenxiu Liu, Yue Wang, Hengtao Song, Dong Xiao, Chao Zhai, Nan Jiang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shuhan WuDepartment of Surgical Oncology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China.
Wenjun ShuDepartment of Surgical Oncology, 3201 Hospital, Hanzhong, Shaanxi, 723000, China.
Xulong ZhuDepartment of Surgical Oncology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China.
Yong Mei ChenCollege of Bioresources Chemical and Materials Engineering, National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi University of Science & Technology, Xi'an, Shaanxi, 710021, China.
Zhenxiu LiuCollege of Bioresources Chemical and Materials Engineering, National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi University of Science & Technology, Xi'an, Shaanxi, 710021, China.
Yue WangDepartment of Surgical Oncology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China.
Hengtao SongDepartment of General Surgery, Ankang Hospital of Traditional Chinese Medicine, Ankang, Shaanxi, 725000, China.
Dong XiaoDepartment of Surgical Oncology, 3201 Hospital, Hanzhong, Shaanxi, 723000, China.
Chao ZhaiDepartment of Surgical Oncology, 3201 Hospital, Hanzhong, Shaanxi, 723000, China.
Nan JiangDepartment of Surgical Oncology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China.
Jianhui LiDepartment of Surgical Oncology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soft tissue defects require the application of adipose tissue reconstruction techniques; however, these approaches often face challenges such as low survival rates due to mechanical pressure and inadequate blood supply. This study presents the development of an injectable, self-healing polysaccharide hydrogel designed for the slow release of basic fibroblast growth factor (b-FGF) that utilizes oxidized hyaluronic acid (OHA) and carbohydrazide-modified gelatin (Gel-CDH) as foundational components. The hydrogel is characterized by an optimal pore size, porosity, mechanical properties, and degradation behavior, in addition to excellent biocompatibility, all of which facilitate adipose tissue growth.

Indexed as

Adipose tissue engineeringAutologous fat graftingGelatinHyaluronic acidInjectable self-healing hydrogel

Identifiers

PMID42903678
PMCPMC13682190

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.