ArticlePhysics and imaging in radiation oncology2026
Evidence-based design of a patient-specific quality assurance program through retrospective analysis of pretreatment and
Article in Physics and imaging in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and purpose: As radiotherapy techniques become increasingly complex, patient-specific quality assurance (PSQA) must evolve to detect a broad spectrum of potential failure modes across the treatment chain. This study presents a extensive evaluation of a multi-modal PSQA program by assessing its ability to detect clinically relevant failure modes and quantifying its efficacy. Materials and Methods: A five-year retrospective analysis was conducted of an integrated PSQA program implemented at Maastro, combining secondary dose calculations, log-file based verification, and Electronic Portal Dosimetry (EPD) in both pretreatment and Results: A total of 18,558 treatment plans were analyzed in the pretreatment workflow and 1817 treatment plans in the Conclusions: This retrospective analysis demonstrated that a comprehensive framework incorporating independent, purpose-specific PSQA methods is essential to detect a wide range of treatment deviations. Combining complementary methods improves the reliability and interpretability of results. The clinical impact of a PSQA program can be further enhanced by adopting more clinically meaningful evaluation metrics and using the results to guide the optimization of new treatment strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.