ArticleCureus2026
Dosimetric Comparison of One-, Two-, Three-, and Four-Arc Volumetric Modulated Arc Therapy Plans in Cervical Carcinoma: Evaluation of Plan Quality, Organ-at-Risk Sparing, and Treatment Efficiency.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Background Volumetric modulated arc therapy (VMAT) has transformed the delivery of pelvic radiotherapy in cervical carcinoma, enabling precise dose conformity around critical organs while maintaining efficient treatment delivery. One important planning consideration that remains insufficiently explored is the optimal number of arcs required for achieving the best dosimetric outcome. This study was designed to address that question by directly comparing one-, two-, three-, and four-arc configurations within the same patient cohort. Methods Eleven patients with cervical carcinoma receiving external beam radiotherapy to 50 Gy in 25 fractions were included. Four separate VMAT plans were generated for each patient on the Eclipse treatment planning system (version 17.0.1, Varian Medical Systems, Inc., Palo Alto, CA, USA), differing only in the number of arcs employed. Plans were assessed for conformity index (CI), homogeneity index (HI), monitor unit (MU) output, and dose to the bladder, rectum, bowel, pelvic bone marrow, and bilateral femoral heads. Results Target conformity did not differ significantly across arc configurations (median CI, 0.83 for all arcs; Friedman X
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