Evidence map›Paper›PMID 42903523›Full record

ArticlehLife2025

Personalized bacteriophage therapy for chronic biliary tract

Na Li, Linlin Li, Bo He, Dandan Li, Wenting Jin, Yuan Wu, Beidi Zhu, Mengjun Cheng, Nannan Wu, Demeng Tan and 12 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in hLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Na LiDepartment of Infectious Diseases, Zhongshan Hospital Fudan University, Shanghai, China.
Linlin LiShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Bo HeDepartment of Microbiology, College of Basic Medical Sciences, Key Laboratory of Microbial Engineering Under the Educational Committee in Chongqing, Army Medical University, Chongqing, China.
Dandan LiDepartment of Infectious Diseases, Zhongshan Hospital Fudan University, Shanghai, China.
Wenting JinDepartment of Infectious Diseases, Zhongshan Hospital Fudan University, Shanghai, China.
Yuan WuDepartment of Infectious Diseases, Zhongshan Hospital Fudan University, Shanghai, China.
Beidi ZhuDepartment of Infectious Diseases, Zhongshan Hospital Fudan University, Shanghai, China.
Mengjun ChengShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Nannan WuFudan University Phage Institute, Zhongshan Hospital Fudan University, Shanghai, China.
Demeng TanShanghai Institute of Phage, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jue PanDepartment of Infectious Diseases, Zhongshan Hospital Fudan University, Shanghai, China.
Chunmei ZhouDepartment of Laboratory Medicine, Zhongshan Hospital Fudan University, Shanghai, China.
Rong BaoDepartment of Laboratory Medicine, Zhongshan Hospital Fudan University, Shanghai, China.
Hao WuDepartment of Gastroenterology, Zhongshan Hospital Fudan University, Shanghai, China.
Wen ZhangDepartment of Interventional Radiology, Zhongshan Hospital Fudan University, Shanghai, China.
Ming LiDepartment of Microbial Physiological & Metabolic Engineering, State Key Laboratory of Microbial Diversity and Innovative Utilization, Chinese Academy of Sciences, Beijing, China.
Zhuojun ZhongDepartment of Microbiology, College of Basic Medical Sciences, Key Laboratory of Microbial Engineering Under the Educational Committee in Chongqing, Army Medical University, Chongqing, China.
Jiazhen LiuDepartment of Microbiology, College of Basic Medical Sciences, Key Laboratory of Microbial Engineering Under the Educational Committee in Chongqing, Army Medical University, Chongqing, China.
Jianglin LiaoDepartment of Microbiology, College of Basic Medical Sciences, Key Laboratory of Microbial Engineering Under the Educational Committee in Chongqing, Army Medical University, Chongqing, China.
Tongyu ZhuFudan University Phage Institute, Zhongshan Hospital Fudan University, Shanghai, China.
Bijie HuDepartment of Infectious Diseases, Zhongshan Hospital Fudan University, Shanghai, China.
Shuai LeDepartment of Microbiology, College of Basic Medical Sciences, Key Laboratory of Microbial Engineering Under the Educational Committee in Chongqing, Army Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biliary tract infections (BTIs) present a significant therapeutic challenge, particularly in the face of increasing antimicrobial resistance. Bacteriophages, viruses that target and destroy bacteria, offer the potential for treating severe bacterial infections, although their use in BTIs has been limited. We describe an 88-year-old female with a complex and recurrent BTI caused by multiple bacteria, including multidrug-resistant

Indexed as

biliary tract infectionsphage therapyPseudomonas aeruginosa

Identifiers

PMID42903523
PMCPMC13681625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.