Evidence map›Paper›PMID 42903453›Full record

ArticleFrontiers in bioengineering and biotechnology2026

A multi-step sequential pretreatment for boosting biomass conversion.

Weikang Teng, Hai Cheng, Yunni Zhan, Huiyang Bian, Fangmin Liang, Tongqi Yuan, Chen Huang, Guigan Fang, Hongbin Li, Xuelian Zhou

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In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Weikang Teng *State Key Laboratory for Development and Utilization of Forest Food Resources, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, China.
Hai Cheng *State Key Laboratory for Development and Utilization of Forest Food Resources, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, China.
Yunni ZhanState Key Laboratory for Development and Utilization of Forest Food Resources, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, China.
Huiyang BianInternational Innovation Center for Forest Chemicals and Materials, Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing, China.
Fangmin LiangState Key Laboratory for Development and Utilization of Forest Food Resources, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, China.
Tongqi YuanBeijing Key Laboratory of Lignocellulosic Chemistry, Beijing Forestry University, Beijing, China.
Chen HuangState Key Laboratory for Development and Utilization of Forest Food Resources, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, China.
Guigan FangState Key Laboratory for Development and Utilization of Forest Food Resources, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, China.
Hongbin LiState Key Laboratory for Development and Utilization of Forest Food Resources, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, China.
Xuelian ZhouState Key Laboratory for Development and Utilization of Forest Food Resources, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to overcome the structural recalcitrance of lignocellulosic biomass and improve the economic viability of biorefineries. A multi-step sequential pretreatment strategy combining hydrothermal pretreatment, twin-screw extrusion, and deep eutectic solvent (DES) treatments was developed to effectively deconstruct poplar biomass while recovering high-quality lignin, xylooligosaccharides (XOS), and fermentable sugars.The results demonstrated that this integrated approach achieved exceptional pretreatment performance, with 89.7% delignification and 85.3% xylan removal. The strategy enabled near-complete cellulose enzymatic hydrolysis at a low enzyme loading (15 FPU/g) and achieved a 45.7% XOS yield. Furthermore, the process yielded high-purity lignin (99.9%) with an 81.5% recovery rate,characterized by reduced molecular weight, enhanced antioxidant activity (IC

Indexed as

antioxidant activitydeep eutectic solventsenzymatic hydrolysisligninpoplar

Identifiers

PMID42903453
PMCPMC13680876

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.