Evidence map›Paper›PMID 42903368›Full record

ArticleCureus2026

Perceived Impact of Cutaneous Hyperpigmentation After Venous Procedures on Patient Self-Esteem: An Observational, Retrospective, Descriptive, Single-Center Case Series.

Brenno Augusto S Mello Netto, Eduardo Zeilmann, Gilmar S Santos, Lucas Sarcinelli Alencar, João Pedro Hemerly, Vinicius Berro Natal, Diana De Oliveira Frauches

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brenno Augusto S Mello NettoVascular Surgery, Seabra Excelencia Vascular, Vitória, BRA.
Eduardo ZeilmannVascular Surgery, Instituto de Flebologia Moderna, Itajaí, BRA.
Gilmar S SantosVascular Surgery, Vein Clinic, Salvador, BRA.
Lucas Sarcinelli AlencarVascular Surgery, Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória, Vitória, BRA.
João Pedro HemerlyMedicine, Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória, Vitória, BRA.
Vinicius Berro NatalSurgery, Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória, Vitória, BRA.
Diana De Oliveira FrauchesMedicine, Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória, Vitória, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveCutaneous hyperpigmentation following venous procedures is commonly regarded as an aesthetic complication of limited clinical relevance. Its effect on patients' self-esteem and aesthetic perception, however, remains underexplored in the medical literature. This study aimed to describe the perceived impact of hyperpigmentation on self-esteem among patients who developed cutaneous hyperpigmentation after venous procedures. MATERIALS AND

methodsThis was a retrospective, descriptive, single-center case series including a total of 91 consecutive patients with cutaneous hyperpigmentation following venous procedures who were treated between 2019 and 2025 at a specialized private vascular clinic. Data were extracted from a structured, non-validated questionnaire routinely applied in clinical practice, covering sociodemographic and clinical variables, aesthetic perception, and a self-reported rating of the perceived impact of hyperpigmentation on self-esteem (none, mild, moderate, or high). Variables were summarized using absolute and relative frequencies.

resultsOf the 91 patients included in the study, most were female (n=85, 93.4%), aged 30-49 years (n=49, 53.8%), had completed higher or postgraduate education (n=71, 78.0%), and had Fitzpatrick skin phototype III or IV (n=81, 89.0%). All lesions were located on the lower limbs, most frequently on the lateral (n=29, 31.9%) and medial (n=18, 19.8%) thigh. Hyperpigmentation had been present for up to six months in 89 patients (97.8%) and most commonly followed foam sclerotherapy (n=44, 48.4%). Every participant reported some degree of impact on self-esteem, rated as moderate in 35 (38.5%) and high in 46 (50.5%). Clothing was intentionally used to conceal the affected area at least occasionally by 86 patients (94.5%) and frequently or always by 56 (61.5%). Among the 89 patients whose hyperpigmentation followed varicose vein treatment, 72 (80.9%) considered the hyperpigmentation aesthetically worse than the varicose veins themselves. Most patients (n=79, 86.8%) expected at least 75% lightening of the lesions with the current treatment.

conclusionsIn this case series, impaired self-esteem, concealment behaviors, a greater aesthetic burden attributed to hyperpigmentation than to the underlying venous disease, and high treatment expectations were consistently reported. Taken together, these findings highlight the relevance of residual hyperpigmentation to the patient's subjective experience and support the systematic use of patient-reported outcomes in the planning and evaluation of the outcomes of venous procedures. The findings should be interpreted in light of the retrospective design, single private-center setting, the characteristics of the sample, and the use of a questionnaire without psychometric validation.

Indexed as

body imagecase serieshyperpigmentationpatient-reported outcome measurespost-sclerotherapy hyperpigmentationsclerotherapyself-esteemvaricose veinsvenous disease

Identifiers

PMID42903368
PMCPMC13681244

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.