Evidence map›Paper›PMID 42903288›Full record

ArticlePlastic and reconstructive surgery. Global open2026

Serasynth Mesh BR Pocket in Prepectoral Direct-to-implant and Tissue-expander Breast Reconstruction: A Retrospective Single-center Analysis.

Florian Wimmer, Alexander Panzirsch, Wolfgang Hitzl, Gabriel Djedovic

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Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Florian WimmerFrom the Department of Plastic, Reconstructive and Aesthetic Surgery, Hospital of the Brothers of St. John of God, Paracelsus Medical University, Salzburg, Austria.
Alexander PanzirschDepartment of Plastic Surgery, Community Hospital Feldkirch, Feldkirch, Austria.
Wolfgang HitzlDepartment of Ophthalmology and Optometry, Paracelsus Medical University Salzburg, Salzburg, Austria.
Gabriel DjedovicDepartment of Plastic Surgery, Community Hospital Feldkirch, Feldkirch, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prepectoral implant-based breast reconstruction after nipple-sparing mastectomy or skin-sparing mastectomy has already shown several advantages. Synthetic meshes are often used as a supportive layer to achieve satisfying and stable results. We present our data using Serasynth Mesh BR Pocket, a fully dissolvable, ready-to-use mesh pocket. Methods: Between December 2021 and August 2023, a single-center retrospective study evaluated 53 breast reconstructions (43 patients) for short-term complications. Complications were classified as major (requiring revision surgery) or minor (managed conservatively). All patients underwent nipple-sparing mastectomy or skin-sparing mastectomy followed by direct-to-implant or direct-to-expander reconstruction using Serasynth Mesh BR Pocket. The minimum follow-up was 4 weeks. Results: Of 53 breasts, 44 (83%) required no further surgical intervention, with a mean follow-up of 10 months (range 1-20, mo). Major complications occurred in 9 breasts (17%), and minor complications occurred in 13 (24.5%). Implant loss (13.2%) was primarily due to necrosis (7.5%). A higher body mass index (≥27 kg/m Conclusions: Serasynth Mesh BR Pocket demonstrates a favorable safety profile in prepectoral breast reconstruction, even in a high-risk cohort with substantial radiotherapy exposure. Outcomes are comparable to those of other synthetic meshes, with the added benefit of full resorbability. Careful patient selection, considering body mass index, soft-tissue quality, and lymph node dissection, is essential to optimize results.

Identifiers

PMID42903288
PMCPMC13680911

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