ArticleFrontiers in immunology2026
Clinical, immunological, and radiological characteristics of pulmonary involvement in childhood-onset primary Sjögren's syndrome: a single-center retrospective study.
Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To describe pulmonary involvement in childhood-onset primary Sjögren's syndrome (cSS). Methods: This retrospective study included 17 children with cSS diagnosed at Jiangxi Provincial Children's Hospital between August 2021 and August 2025. Patients were classified by baseline chest high-resolution computed tomography (HRCT)as normal CT (n=8) or abnormal CT (n=9); among patients with abnormal CT, 5 had interstitial lung involvement. Clinical, laboratory, radiological, and outcome data were compared. Results: Among 17 children, 14 were female (82.4%), and the mean age at onset was 10.83 ± 3.12 years. Abnormal chest CT findings were detected in 9 patients (52.9%). Age at onset was younger in the abnormal CT group than in the normal CT group (9.37 ± 2.67 vs. 12.48 ± 2.88 years, Conclusion: Pulmonary abnormalities were common in children with cSS. Younger onset and aberrant T/B lymphocyte subsets showed exploratory associations with pulmonary involvement, which appeared mainly inflammatory and demonstrated favorable radiological evolution during follow-up.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.